Gene: MELTF
Official Full Name: melanotransferrinprovided by HGNC
Gene Summary: The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36650 | MELTF Knockout cell line (HeLa) | Human | MELTF | 1:3~1:6 | Negative | Online Inquiry |
KO36651 | MELTF Knockout cell line (HCT 116) | Human | MELTF | 1:2~1:4 | Negative | Online Inquiry |
KO36652 | MELTF Knockout cell line (HEK293) | Human | MELTF | 1:3~1:6 | Negative | Online Inquiry |
KO36653 | MELTF Knockout cell line (A549) | Human | MELTF | 1:3~1:4 | Negative | Online Inquiry |
MELTF Gene Knockout Cell Lines represent a revolutionary tool in genetic research, specifically designed to facilitate the study of gene function and regulation in mammalian systems. These cell lines are engineered using advanced CRISPR-Cas9 gene editing technology, which allows for the targeted disruption of specific genes, leading to highly controlled and reproducible knockout models. By providing researchers with the ability to create precise genetic modifications, MELTF cell lines enhance our understanding of complex biological processes and disease mechanisms.
The key mechanism underlying MELTF Gene Knockout Cell Lines involves the use of guiding RNA sequences that direct the Cas9 nuclease to the target gene, resulting in double-strand breaks that are repaired through non-homologous end joining, ultimately leading to gene inactivation. This precise gene disruption is instrumental for elucidating gene function, characterizing cellular pathways, and providing insights into therapeutic targets for disease conditions such as cancer, metabolic disorders, and neurological diseases.
The scientific importance of MELTF Gene Knockout Cell Lines extends to both basic and applied research. In clinical settings, these cell lines allow for the development of disease models that can mimic human pathophysiology, contributing to drug discovery and therapeutic development. Researchers can utilize these models for high-throughput screening and validation of genetic targets, significantly accelerating the pace of translational research.
What sets MELTF Gene Knockout Cell Lines apart from alternative products is their superior specificity, ease of use, and the broad range of available genetic targets. Unlike traditional knockout techniques, which may involve cumbersome methods such as homologous recombination, MELTF cell lines streamline the gene knockout process, reducing time and resources needed for experimental setups. Their robustness in various experimental conditions makes them a reliable choice for labs focused on cutting-edge research.
For researchers and clinicians, investing in MELTF Gene Knockout Cell Lines promises to enhance experimental accuracy and yield valuable insights into gene function, ultimately driving innovation and improving patient care. With years of expertise in producing high-quality biological products, our company is dedicated to providing researchers with the critical tools needed for scientific advancement, ensuring you have the best resources at your disposal.
Please note that all services are for research use only. Not intended for any clinical use.
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