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MEGF9 Knockout Cell Lines

Gene: MEGF9

Official Full Name: multiple EGF like domains 9provided by HGNC

Gene Summary: Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be located in basement membrane and membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38078 MEGF9 Knockout cell line (HeLa) Human MEGF9 1:3~1:6 Negative Online Inquiry
KO38079 MEGF9 Knockout cell line (HCT 116) Human MEGF9 1:2~1:4 Negative Online Inquiry
KO38080 MEGF9 Knockout cell line (HEK293) Human MEGF9 1:3~1:6 Negative Online Inquiry
KO38081 MEGF9 Knockout cell line (A549) Human MEGF9 1:3~1:4 Negative Online Inquiry

Background

MEGF9 Gene Knockout Cell Lines are engineered cellular models designed to study the impact of the MEGF9 gene's absence on various biological processes. Created using advanced CRISPR/Cas9 technology, these cell lines provide a robust platform for investigating the role of MEGF9 in cellular signaling, development, and disease pathology. By precisely knocking out the MEGF9 gene, researchers can discern the gene's contributions to specific phenotypic characteristics, cellular responses, and potential therapeutic targets.

The core mechanism of the MEGF9 Gene Knockout Cell Lines relies on selective gene disruption, which leads to the loss of MEGF9 protein expression. This alteration facilitates the exploration of downstream effects on molecular pathways involved in cell proliferation, differentiation, and apoptosis. Such insights are critical for understanding the gene's role in both normal physiological functions and the pathogenesis of various diseases, particularly in neurobiology and cancer research.

The scientific importance of these cell lines cannot be overstated, as they allow researchers to systematically explore gene function through loss-of-function studies. Their versatility makes them suitable for a range of applications, from basic research to preclinical studies assessing drug efficacy and toxicity. Unlike traditional models that may not accurately mimic human disease states, MEGF9 Gene Knockout Cell Lines offer precise, human-relevant data, significantly enhancing translational research outcomes.

In addition to their experimental precision, these cell lines are manufactured with strict quality control measures, ensuring high consistency and reproducibility across experiments. This reliability sets them apart from alternative models that may present variable results. Moreover, our MEGF9 Gene Knockout Cell Lines come with comprehensive support and resources, including detailed protocol guides and troubleshooting assistance to help users achieve optimal results.

In conclusion, our commitment to scientific innovation and excellence in cell line development ensures that researchers and clinicians have access to the tools necessary for groundbreaking discoveries. The MEGF9 Gene Knockout Cell Lines exemplify our dedication to providing high-quality, reliable biological products that advance research and improve clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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