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MBIP Knockout Cell Lines

Gene: MBIP

Official Full Name: MAP3K12 binding inhibitory protein 1provided by HGNC

Gene Summary: Enables identical protein binding activity and protein kinase inhibitor activity. Involved in several processes, including positive regulation of JNK cascade; regulation of cell division; and regulation of macromolecule metabolic process. Located in cytosol; nucleolus; and nucleoplasm. Part of ATAC complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22403 MBIP Knockout cell line (HeLa) Human MBIP 1:3~1:6 Negative Online Inquiry
KO22404 MBIP Knockout cell line (HCT 116) Human MBIP 1:2~1:4 Negative Online Inquiry
KO22405 MBIP Knockout cell line (HEK293) Human MBIP 1:3~1:6 Negative Online Inquiry
KO22406 MBIP Knockout cell line (A549) Human MBIP 1:3~1:4 Negative Online Inquiry

Background

MBIP Gene Knockout Cell Lines are genetically engineered cell lines designed to lack the expression of the MBIP gene, a critical regulator within various cellular signaling pathways relevant to oncogenesis and cellular metabolism. This powerful tool allows researchers to investigate the functional implications of MBIP deficiency, contributing to our understanding of its role in processes such as cell proliferation, apoptosis, and gene expression modulation.

These knockout cell lines function by employing CRISPR-Cas9 technology to create specific gene disruptions, effectively creating a model system where researchers can observe the phenotypic consequences of the absence of MBIP. The high efficiency of this gene-editing technique ensures that the resultant cell lines maintain genetic stability while providing a reliable platform for further experimentation.

The scientific importance of MBIP Gene Knockout Cell Lines is underscored by their diverse applications in both research and clinical settings, including cancer biology, drug development, and gene function studies. Researchers investigating signaling pathways involved in cancer can utilize these cell lines to understand the mechanisms of tumorigenesis and explore potential therapeutic interventions targeting MBIP-related pathways.

Compared to alternative models, such as wild-type cell lines or traditional knockout models that may carry unwanted mutations, MBIP Gene Knockout Cell Lines offer unparalleled specificity and reproducibility. This precision makes them an essential asset for any laboratory focused on cutting-edge genetic research. Furthermore, the ease of use and consistent cell line performance enables researchers to obtain results faster, streamlining their experiments.

For researchers and clinicians dedicated to unraveling complex biological mechanisms, MBIP Gene Knockout Cell Lines represent a vital resource, fostering advanced exploration into the roles of specific genes in health and disease. Our company is committed to delivering high-quality, innovative biological products, backed by extensive expertise in gene editing technologies, enabling our clients to push the boundaries of scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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