Gene: MAPRE3
Official Full Name: microtubule associated protein RP/EB family member 3provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30101 | MAPRE3 Knockout cell line (HeLa) | Human | MAPRE3 | 1:3~1:6 | Negative | Online Inquiry |
KO30102 | MAPRE3 Knockout cell line (HCT 116) | Human | MAPRE3 | 1:2~1:4 | Negative | Online Inquiry |
KO30103 | MAPRE3 Knockout cell line (HEK293) | Human | MAPRE3 | 1:3~1:6 | Negative | Online Inquiry |
KO30104 | MAPRE3 Knockout cell line (A549) | Human | MAPRE3 | 1:3~1:4 | Negative | Online Inquiry |
MAPRE3 Gene Knockout Cell Lines are specifically engineered cellular models that enable researchers to study the loss-of-function effects associated with the MAPRE3 gene. This gene encodes the microtubule-associated protein RP3, which plays crucial roles in cellular processes such as microtubule stabilization, cell signaling, and transport mechanisms. By utilizing CRISPR-Cas9 genome editing technology, these knockout cell lines provide a precise genetic modification that completely abolishes MAPRE3 expression, allowing for an in-depth investigation into its biological functions and involvement in cellular pathways.
One of the primary functions of MAPRE3 is its involvement in regulating microtubule dynamics, which are vital for cellular shape, division, and intracellular transport. By knocking out MAPRE3, scientists can elucidate its role in oncogenic processes and cellular responses to stressors, thereby providing valuable insights into cancer biology and drug resistance mechanisms. Such capabilities make the MAPRE3 Gene Knockout Cell Lines indispensable tools in both fundamental research and translational applications, particularly in understanding complex diseases where microtubule stabilization is disrupted.
Compared to other available models, the MAPRE3 Gene Knockout Cell Lines stand out due to their specificity and reliability. Unlike transient transfection methods or RNA interference, which may lead to incomplete or temporary gene suppression, these knockout cell lines allow for stable and long-term studies of gene function in a variety of experimental conditions. Furthermore, the uniformity of the knockout phenotype ensures reproducibility in experimental results, which is critical for the advancement of scientific knowledge.
For researchers and clinicians, investing in MAPRE3 Gene Knockout Cell Lines accelerates discovery processes, yielding faster results in experimental setups and enabling the identification of novel therapeutic targets. By providing a robust and versatile research tool, we empower the scientific community to unravel the complexities of gene function and disease.
Our company specializes in developing high-quality biological products, leveraging advanced genetic engineering technologies to meet the evolving needs of researchers worldwide. We pride ourselves on delivering innovative solutions that support cutting-edge research and drive advancements in personalized medicine and biotechnology.
Please note that all services are for research use only. Not intended for any clinical use.
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