Gene: MAN2B2
Official Full Name: mannosidase alpha class 2B member 2provided by HGNC
Gene Summary: Predicted to enable alpha-mannosidase activity. Predicted to be involved in mannose metabolic process and oligosaccharide catabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29460 | MAN2B2 Knockout cell line (HeLa) | Human | MAN2B2 | 1:3~1:6 | Negative | Online Inquiry |
KO29461 | MAN2B2 Knockout cell line (HCT 116) | Human | MAN2B2 | 1:2~1:4 | Negative | Online Inquiry |
KO29462 | MAN2B2 Knockout cell line (HEK293) | Human | MAN2B2 | 1:3~1:6 | Negative | Online Inquiry |
KO29463 | MAN2B2 Knockout cell line (A549) | Human | MAN2B2 | 1:3~1:4 | Negative | Online Inquiry |
MAN2B2 Gene Knockout Cell Lines are genetically engineered models that facilitate the study of the MAN2B2 gene, responsible for encoding the enzyme mannosidase Beta 2. This enzymatic activity plays a crucial role in glycoprotein processing and degradation, making these cell lines indispensable tools for unraveling the complex biological pathways influenced by glycan metabolism and their implications in diseases such as lysosomal storage disorders.
The key functionality of MAN2B2 Gene Knockout Cell Lines lies in their precise manipulation of the MAN2B2 gene, resulting in the absence of the associated protein product. This knockout allows researchers to investigate the biochemical and physiological consequences of MAN2B2 deficiency. By employing these cell lines in various assays, scientists can elucidate the cellular mechanisms underlying glycan processing alterations and their role in cellular function, especially in the context of genetic disorders and potential therapeutic interventions.
The scientific importance of these cell lines extends to both fundamental research and clinical applications. They are invaluable for drug discovery efforts aimed at developing novel treatments for glycosylation disorders by providing a robust platform for testing potential pharmacological agents. Furthermore, the insights obtained from using MAN2B2 knockout models can significantly contribute to understanding the pathophysiology of related diseases, thereby facilitating the development of targeted therapies.
One of the primary advantages of our MAN2B2 Gene Knockout Cell Lines is their specificity and reliability compared to alternative models. While traditional methods of gene manipulation can result in off-target effects or incomplete knockout, our cell lines offer precise gene editing, ensuring accurate representation of MAN2B2 deficiency. This specificity translates into more valid experimental outcomes, as researchers can manipulate and study these cells with confidence regarding the genetic alterations involved.
The value of MAN2B2 Gene Knockout Cell Lines to researchers, clinicians, and the pharmaceutical industry cannot be overstated. By utilizing these advanced models, users can unlock new avenues of research that may lead to breakthroughs in understanding glycan-related pathologies and developing effective therapeutic strategies.
Our company specializes in producing high-quality biological products supported by extensive research and development expertise. We provide cutting-edge tools that empower scientists to advance their understanding of complex biological systems, and the MAN2B2 Gene Knockout Cell Lines exemplify our commitment to facilitating impactful scientific discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.