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LSR Knockout Cell Lines

Gene: LSR

Official Full Name: lipolysis stimulated lipoprotein receptorprovided by HGNC

Gene Summary: Predicted to be involved in several processes, including establishment of skin barrier; protein localization to tricellular tight junction; and tricellular tight junction assembly. Predicted to act upstream of or within maintenance of blood-brain barrier. Located in plasma membrane and tight junction. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22379 LSR Knockout cell line (HeLa) Human LSR 1:3~1:6 Negative Online Inquiry
KO22380 LSR Knockout cell line (HCT 116) Human LSR 1:2~1:4 Negative Online Inquiry
KO22381 LSR Knockout cell line (HEK293) Human LSR 1:3~1:6 Negative Online Inquiry
KO22382 LSR Knockout cell line (A549) Human LSR 1:3~1:4 Negative Online Inquiry

Background

LSR Gene Knockout Cell Lines represent a pioneering advancement in genetic research, specifically designed to facilitate the study of the function of the LSR gene and its role in various biological processes. These cell lines have been meticulously engineered using CRISPR-Cas9 technology, allowing for precise and specific disruption of the LSR gene. This knockout approach enables researchers to investigate the phenotypic consequences of LSR gene loss, providing insights into its contributions to cell signaling, inflammation, and other critical cellular functions.

The key mechanism of these cell lines lies in the targeted editing of the genomic sequence of the LSR gene. By creating a complete knockout, the cell lines enable the evaluation of changes in cellular behavior, protein expression profiles, and signaling pathways that are directly influenced by the absence of LSR functionality. This level of targeted genetic manipulation is critical for elucidating the gene's role in health and disease.

Scientifically, LSR Gene Knockout Cell Lines have broad applications in both research and clinical contexts. They can be instrumental in drug discovery processes, functional genomics studies, and translational medicine initiatives, where understanding gene function is essential for developing novel therapeutic strategies. Moreover, they serve as valuable tools in the study of various pathological conditions, including cancer, metabolic disorders, and cardiovascular diseases.

One of the significant advantages of LSR Gene Knockout Cell Lines compared to traditional knockdown approaches is their permanence in gene disruption. This durability allows for long-term studies and reduces variability associated with transient or partial gene silencing techniques. Additionally, the use of CRISPR-Cas9 ensures high specificity and efficiency, minimizing off-target effects that may confound experimental outcomes.

For researchers and clinicians seeking to advance their understanding of gene function, the LSR Gene Knockout Cell Lines provide an unparalleled resource. They empower scientists to perform comprehensive analyses that can lead to impactful discoveries in gene therapy, biomarker development, and personalized medicine.

Our company specializes in the development of high-quality biological products tailored to meet the needs of cutting-edge research. With extensive expertise in gene editing technologies, we are committed to providing innovative solutions that enhance scientific discovery and advance translational applications.

Please note that all services are for research use only. Not intended for any clinical use.

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