Gene: LRRC61
Official Full Name: leucine rich repeat containing 61provided by HGNC
Gene Summary: Predicted to enable alpha-tubulin binding activity and dynein heavy chain binding activity. Predicted to be involved in outer dynein arm assembly. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16443 | LRRC61 Knockout cell line (HeLa) | Human | LRRC61 | 1:3~1:6 | Negative | Online Inquiry |
KO16444 | LRRC61 Knockout cell line (HCT 116) | Human | LRRC61 | 1:2~1:4 | Negative | Online Inquiry |
KO16445 | LRRC61 Knockout cell line (HEK293) | Human | LRRC61 | 1:3~1:6 | Negative | Online Inquiry |
LRRC61 Gene Knockout Cell Lines are specialized laboratory tools engineered to facilitate the study of the LRRC61 gene, which encodes a protein implicated in cellular signaling pathways and various biological processes, including immune response regulation and cell differentiation. These cell lines are derived from well-characterized parent cell types, enabling researchers to accurately assess the functional consequences of gene deletion on cellular behavior.
The key mechanism of action involves the targeted disruption of the LRRC61 gene using CRISPR/Cas9 technology, which results in a loss-of-function phenotype. This precise gene editing allows researchers to explore the biological roles and regulatory networks associated with LRRC61 in various contexts, such as cancer biology, neurobiology, and immunology. By utilizing these knockout cell lines, scientists can conduct thorough investigations into gene function, including downstream signaling pathways and potential compensatory mechanisms that arise due to gene loss.
The scientific importance of LRRC61 Gene Knockout Cell Lines cannot be overstated. They are invaluable in both research and clinical applications, offering insights into disease mechanisms and potential therapeutic targets. For example, understanding the role of LRRC61 can lead to advancements in treating autoimmune disorders or enhancing cancer immunotherapies.
Compared to alternative models, such as overexpression systems or wild-type cell lines, these knockout models provide a clear view of gene function by eliminating confounding variables that can arise from gene redundancy. This specificity enables more reliable data interpretation and validation of findings, setting them apart as a superior choice for researchers focused on elucidating gene function.
For researchers and clinicians aiming to deepen their understanding of cellular processes or develop new therapeutic strategies, LRRC61 Gene Knockout Cell Lines represent a robust and versatile experimental platform. Our company is committed to providing high-quality biological products backed by extensive expertise and support, ensuring that our clients have the tools they need to advance their scientific endeavors effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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