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LRMDA Knockout Cell Lines

Gene: LRMDA

Official Full Name: leucine rich melanocyte differentiation associatedprovided by HGNC

Gene Summary: This gene encodes a leucine-rich repeat protein. The encoded protein is thought to play a role in melanocyte differentiation. Mutations in this gene have been associated with autosomal recessive oculocutaneous albinism 7 (OCA7). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25306 LRMDA Knockout cell line (HeLa) Human LRMDA 1:3~1:6 Negative Online Inquiry
KO25307 LRMDA Knockout cell line (HCT 116) Human LRMDA 1:2~1:4 Negative Online Inquiry
KO25308 LRMDA Knockout cell line (HEK293) Human LRMDA 1:3~1:6 Negative Online Inquiry
KO25309 LRMDA Knockout cell line (A549) Human LRMDA 1:3~1:4 Negative Online Inquiry

Background

LRMDA Gene Knockout Cell Lines are advanced cellular models specifically engineered to exhibit the complete absence of the LRMDA (Leucine Rich Motif Containing 1) gene. By employing the CRISPR-Cas9 gene-editing technology, these cell lines facilitate the precise disruption of the LRMDA gene, allowing researchers to investigate its role in various cellular processes and disease states. The mechanism involves targeted alterations in the genomic DNA, leading to gene knockout, which is essential for elucidating the biological significance of LRMDA in cellular function, including proliferation, differentiation, and apoptosis.

The scientific importance of LRMDA gene knockout cell lines lies in their application across numerous fields of research, including oncology, immunology, and neurology. These models provide invaluable insights into the gene's function and the pathways it interacts with, contributing to a better understanding of diseases associated with aberrations in LRMDA expression. In clinical settings, this research could pave the way for novel therapeutic strategies aimed at conditions linked to LRMDA dysregulation, including various cancers and autoimmune disorders.

Compared to other gene knockout models, our LRMDA gene knockout cell lines offer unique advantages such as high efficiency of knockout generation, minimal off-target effects, and reproducibility in experimental results. These features ensure that researchers can trust the reliability and validity of their data, ultimately enhancing the rigor of scientific investigations.

For researchers and clinicians, the value of LRMDA gene knockout cell lines is evident: they represent a cutting-edge tool for dissecting complex biological mechanisms and fostering innovations in drug development. With an emphasis on meticulous design and validation, our company brings unparalleled expertise in genetic engineering and cell line development, ensuring that our customers receive top-tier products tailored to advance their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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