Gene: LRCH3
Official Full Name: leucine rich repeats and calponin homology domain containing 3provided by HGNC
Gene Summary: Involved in septin cytoskeleton organization. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24583 | LRCH3 Knockout cell line (HeLa) | Human | LRCH3 | 1:3~1:6 | Negative | Online Inquiry |
KO24584 | LRCH3 Knockout cell line (HCT 116) | Human | LRCH3 | 1:2~1:4 | Negative | Online Inquiry |
KO24585 | LRCH3 Knockout cell line (HEK293) | Human | LRCH3 | 1:3~1:6 | Negative | Online Inquiry |
KO24586 | LRCH3 Knockout cell line (A549) | Human | LRCH3 | 1:3~1:4 | Negative | Online Inquiry |
LRCH3 Gene Knockout Cell Lines are genetically modified cellular models specifically engineered to lack the LRCH3 gene, a pivotal component implicated in numerous cellular processes, including signal transduction, cellular adhesion, and cytoskeleton organization. These knockout cell lines serve as indispensable tools for elucidating the biological functions of LRCH3 and investigating its roles in health and disease.
The primary mechanism by which these cell lines operate revolves around the absence of the LRCH3 protein, allowing researchers to study the consequences of its loss on cell behavior, signaling pathways, and gene expression profiles. By employing techniques such as CRISPR/Cas9 genome editing, the targeted knockout of the LRCH3 gene results in a controlled and reproducible model to explore associated molecular mechanisms. This is particularly beneficial in understanding tumor biology, inflammatory responses, and cellular migration, making them vital resources in translational research.
The scientific significance of LRCH3 Gene Knockout Cell Lines extends into both basic research and clinical applications. They can accelerate discoveries related to cancer research, autoimmune diseases, and cardiovascular conditions by providing insights into potential therapeutic targets and drug responses. Additionally, these models can facilitate the validation of hypotheses at a molecular level, thus streamlining the path from laboratory findings to clinical applications.
What sets LRCH3 Gene Knockout Cell Lines apart from traditional cellular models is their precision and specificity. Researchers can rely on these cell lines to overcome challenges presented by genetic variability and compensatory mechanisms often observed in wild-type models. This specificity enhances experimental reproducibility and contributes to the reliability of data obtained.
For researchers and clinicians alike, the value of LRCH3 Gene Knockout Cell Lines lies in their potential to uncover intricate biological mechanisms relevant to disease pathology and treatment. With robust support from our team of experts in genetic engineering and cell biology, we are committed to equipping the scientific community with high-quality tools that drive innovation and advance therapeutic strategies.
Please note that all services are for research use only. Not intended for any clinical use.
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