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LPCAT1 Knockout Cell Lines

Gene: LPCAT1

Official Full Name: lysophosphatidylcholine acyltransferase 1provided by HGNC

Gene Summary: This gene encodes a member of the 1-acyl-sn-glycerol-3-phosphate acyltransferase family of proteins. The encoded enzyme plays a role in phospholipid metabolism, specifically in the conversion of lysophosphatidylcholine to phosphatidylcholine in the presence of acyl-CoA. This process is important in the synthesis of lung surfactant and platelet-activating factor (PAF). Elevated expression of this gene may contribute to the progression of oral squamous cell, prostate, breast, and other human cancers. [provided by RefSeq, Sep 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16501 LPCAT1 Knockout cell line (HeLa) Human LPCAT1 1:3~1:6 Negative Online Inquiry
KO16502 LPCAT1 Knockout cell line (HCT 116) Human LPCAT1 1:2~1:4 Negative Online Inquiry
KO16503 LPCAT1 Knockout cell line (HEK293) Human LPCAT1 1:3~1:6 Negative Online Inquiry
KO16504 LPCAT1 Knockout cell line (A549) Human LPCAT1 1:3~1:4 Negative Online Inquiry

Background

LPCAT1 Gene Knockout Cell Lines are engineered cellular models that have had the LPCAT1 gene, which encodes for lysophosphatidylcholine acyltransferase 1, systematically disrupted. This gene plays a crucial role in phospholipid metabolism, particularly in the conversion of lysophosphatidylcholine to phosphatidylcholine. The knockout of this gene allows researchers to study the functional consequences of LPCAT1 deficiency, providing deeper insights into cellular lipidomics and their impact on various biological processes.

These cell lines facilitate key investigations into lipid metabolism, innate immunity, and cellular signaling pathways. By bypassing the normal function of LPCAT1, scientists can observe altered cellular behavior, which is crucial for understanding disease mechanisms such as inflammation and cancer. Additionally, using these cell lines can aid in the identification of therapeutic vulnerabilities in cancer cells, enhancing drug discovery and development processes.

One of the primary advantages of LPCAT1 Gene Knockout Cell Lines is their specificity. Compared to traditional methods, such as chemical inhibitors, these cell lines provide a more controlled and consistent environment for studying gene function and cellular responses. Furthermore, they eliminate off-target effects often seen in pharmacological interventions, thus yielding more reliable data for scientific inquiries.

For researchers in the fields of molecular biology, biochemistry, and pharmacology, LPCAT1 Gene Knockout Cell Lines offer a valuable tool for elucidating the roles of lipids in health and disease. Their availability ensures that investigators have access to high-quality models that can accelerate the pace of discovery.

At [Your Company Name], we pride ourselves on delivering cutting-edge biological products that empower researchers and clinicians alike. Our expertise in cellular models ensures that you receive not just a product, but a foundational tool for your scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

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