Gene: LGSN
Official Full Name: lengsin, lens protein with glutamine synthetase domainprovided by HGNC
Gene Summary: This gene encodes a protein with similarity to the GS I members of the glutamine synthetase superfamily. The encoded protein is referred to as a pseudo-glutamine synthetase because it has no glutamine synthesis activity and may function as a chaperone protein. This protein is localized to the lens and may be associated with cataract disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16561 | LGSN Knockout cell line (HeLa) | Human | LGSN | 1:3~1:6 | Negative | Online Inquiry |
KO39173 | LGSN Knockout cell line (A549) | Human | LGSN | 1:3~1:4 | Negative | Online Inquiry |
LGSN Gene Knockout Cell Lines are genetically engineered cell lines designed for the specific ablation of target genes, resulting in a complete loss of gene function. These cell models are indispensable tools in molecular biology and genetics, providing researchers with a means to study gene function, unravel disease mechanisms, and test therapeutic interventions. The knockout process typically employs CRISPR-Cas9 technology, a powerful genome-editing tool that allows for precise modifications to DNA, facilitating the generation of cell lines lacking specific genes of interest.
The key function of LGSN Gene Knockout Cell Lines is to enable researchers to delineate the biological roles of specific genes in various cellular processes, including proliferation, differentiation, and response to stimuli. By systematically knocking out genes, scientists can observe phenotypic changes, elucidate signaling pathways, and validate drug targets. Additionally, these cell lines serve as critical models for studying genetic disorders and assessing the efficacy of novel therapeutics, thereby bridging the gap between bench research and clinical applications.
In research and clinical settings, the scientific importance of LGSN Gene Knockout Cell Lines is underscored by their ability to facilitate high-throughput screening and functional assays, offering insights that are pivotal for drug discovery and development. The unique advantage of LGSN cell lines lies in their customization options, allowing for the knockout of multiple genes in a single cell line, which can lead to more complex and informative studies pertaining to gene interactions and network effects—capabilities that many existing models may not support.
The value of LGSN Gene Knockout Cell Lines to researchers and clinicians is found in their robust reproducibility, ease of use, and the comprehensive data outputs they provide, empowering users to advance their work in genetic manipulation and therapeutic development. With our commitment to innovation and excellence in bioengineering, our company brings decades of expertise in creating reliable, high-quality biological products that propel scientific discovery and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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