Gene: LETMD1
Official Full Name: LETM1 domain containing 1provided by HGNC
Gene Summary: This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28696 | LETMD1 Knockout cell line (HeLa) | Human | LETMD1 | 1:3~1:6 | Negative | Online Inquiry |
KO28697 | LETMD1 Knockout cell line (HCT 116) | Human | LETMD1 | 1:2~1:4 | Negative | Online Inquiry |
KO28698 | LETMD1 Knockout cell line (HEK293) | Human | LETMD1 | 1:3~1:6 | Negative | Online Inquiry |
KO28699 | LETMD1 Knockout cell line (A549) | Human | LETMD1 | 1:3~1:4 | Negative | Online Inquiry |
LETMD1 Gene Knockout Cell Lines are specialized cell lines where the LETMD1 gene has been inactivated through targeted gene editing techniques, such as CRISPR-Cas9. These cell lines serve as vital tools for elucidating the complex functions of the LETMD1 gene, which is implicated in various biological processes including cellular metabolism, signal transduction, and responses to stress. By studying these knockout models, researchers gain insights into the role of LETMD1 in health and disease, contributing to the understanding of its potential associations with pathologies like cancer and metabolic disorders.
The fundamental mechanism by which LETMD1 gene knockout cell lines operate involves the complete elimination or disruption of the LETMD1 protein, providing a platform for comparative analyses against wild-type counterparts. This allows for the dissection of the molecular pathways in which LETMD1 is involved, enabling experiments that can track changes in gene expression, protein interactions, and cellular functions.
Scientifically, these cell lines are of paramount importance for both research and clinical applications. They serve as valuable models for drug discovery, enabling the identification of therapeutic targets by assessing the impact of potential interventions on LETMD1-deficient cells. Furthermore, they are integral in studying gene function, disease modeling, and the validation of genetic therapies.
One significant advantage of LETMD1 Gene Knockout Cell Lines lies in their specificity and reproducibility, which outweigh many existing alternatives. Many conventional models can exhibit variability due to genetic background or residual functions of the targeted genes; however, our knockout lines are rigorously validated to ensure consistent performance across studies. This precision enhances the reliability of experimental results, making data interpretation clearer and outcomes more predictable.
For researchers and clinicians focused on genetic research or translational medicine, investing in LETMD1 Gene Knockout Cell Lines is crucial for advancing scientific knowledge and developing innovative treatment strategies. They provide the robust experimental backbone essential for uncovering the intricate roles genes play in health and disease.
Our company, with years of expertise in providing high-quality biological products, stands committed to empowering scientific advancements through comprehensive tools like LETMD1 Gene Knockout Cell Lines, ensuring that researchers have access to reliable models that facilitate their groundbreaking work.
Please note that all services are for research use only. Not intended for any clinical use.
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