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LDLRAD3 Knockout Cell Lines

Gene: LDLRAD3

Official Full Name: low density lipoprotein receptor class A domain containing 3provided by HGNC

Gene Summary: Predicted to enable amyloid-beta binding activity. Predicted to be involved in receptor-mediated endocytosis. Predicted to act upstream of or within regulation of protein processing. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00674 LDLRAD3 gRNA1-gRNA2 KO plasmid LDLRAD3 $850
KO00849 LDLRAD3 Knockout cell line(293T) Human LDLRAD3 1:3~1:6 Negative Online Inquiry
KO16573 LDLRAD3 Knockout cell line (HeLa) Human LDLRAD3 1:3~1:6 Negative Online Inquiry
KO16574 LDLRAD3 Knockout cell line (HCT 116) Human LDLRAD3 1:2~1:4 Negative Online Inquiry
KO16575 LDLRAD3 Knockout cell line (HEK293) Human LDLRAD3 1:3~1:6 Negative Online Inquiry
KO16576 LDLRAD3 Knockout cell line (A549) Human LDLRAD3 1:3~1:4 Negative Online Inquiry

Background

LDLRAD3 Gene Knockout Cell Lines are genetically modified cell lines designed to eliminate the expression of the LDLRAD3 gene, which encodes for low-density lipoprotein receptor class A domain-containing protein 3. This specific gene is implicated in lipid metabolism, thus providing a valuable tool for researchers exploring the intricate pathways associated with cholesterol regulation and lipoprotein dynamics. By employing CRISPR/Cas9 technology or similar gene-editing techniques, these knockout cell lines effectively silence LDLRAD3, enabling scientists to study the resulting phenotypic changes and dissect the cellular mechanisms influenced by its absence.

The primary function of the LDLRAD3 Gene Knockout Cell Lines lies in their ability to serve as a model for elucidating the role of LDLRAD3 in lipid absorption, transport, and overall metabolic processes. Researchers can utilize these cell lines in various assays to investigate alterations in cellular responses to lipid stimuli, evaluate changes in receptor activity, and explore potential pathways involved in lipid-related disorders. This makes them particularly relevant for studies related to cardiovascular health, metabolic syndrome, and other diseases linked to lipid dysregulation.

The scientific importance of LDLRAD3 Gene Knockout Cell Lines cannot be overstated, as they facilitate groundbreaking research in both academic and clinical settings. By understanding the exact function of LDLRAD3, researchers can better comprehend the broader implications of lipid metabolism and identify potential therapeutic targets for hyperlipidemia and associated conditions.

One of the standout advantages of these knockout cell lines is their specificity and reliability compared to traditional models. Whereas knockdown approaches may only partially silence gene expression, full knockout ensures complete loss of function, providing definitive insights into the biological role of LDLRAD3. Furthermore, our cell lines are extensively characterized, ensuring consistency in experimentation and reproducibility, which is crucial for the rigorous demands of contemporary research.

For researchers, clinicians, and pharmaceutical developers, the LDLRAD3 Gene Knockout Cell Lines offer an invaluable resource in the quest to understand and potentially mitigate the effects of lipid metabolism disorders. They provide an innovative solution for advancing knowledge in the field while also supporting the development of new therapeutic strategies.

Our company prides itself on its expertise in developing high-quality biological products, and these LDLRAD3 Gene Knockout Cell Lines exemplify our commitment to supporting scientific advancement and fostering breakthroughs in health and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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