Gene: KMT5C
Official Full Name: lysine methyltransferase 5Cprovided by HGNC
Gene Summary: SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).[supplied by OMIM, Dec 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24633 | KMT5C Knockout cell line (HeLa) | Human | KMT5C | 1:3~1:6 | Negative | Online Inquiry |
KO24634 | KMT5C Knockout cell line (HCT 116) | Human | KMT5C | 1:2~1:4 | Negative | Online Inquiry |
KO24635 | KMT5C Knockout cell line (HEK293) | Human | KMT5C | 1:3~1:6 | Negative | Online Inquiry |
KO24636 | KMT5C Knockout cell line (A549) | Human | KMT5C | 1:3~1:4 | Negative | Online Inquiry |
KMT5C Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to inactivate the KMT5C gene, which encodes a histone methyltransferase involved in the regulation of gene expression and chromatin dynamics. These knockout cell lines serve as a critical tool for researchers to elucidate the functional roles of KMT5C in various biological processes, including development, differentiation, and cellular response to environmental stimuli.
The primary mechanism of action of KMT5C Gene Knockout Cell Lines involves the disruption of the KMT5C protein product, leading to alteration in histone methylation patterns. This modification influences the transcriptional landscape of the cell, providing insights into how epigenetic regulation contributes to health and disease states. By utilizing these knockout models, researchers can investigate KMT5C's role in cancer biology, stem cell differentiation, and other pathophysiological conditions.
In scientific research and clinical settings, the KMT5C Gene Knockout Cell Lines hold significant importance. They facilitate high-throughput screening for drug development targeting epigenetic mechanisms, as well as aiding in the identification of novel biomarkers for disease progression. The use of these knockout models can expedite the understanding of complex gene functions, ultimately leading to the advancement of therapeutic strategies.
Distinct from other gene knockout models, the KMT5C cell lines offer precise and reliable gene editing, with minimal off-target effects, which enhances the reproducibility and validity of experimental results. Unlike traditional approaches, these cell lines are readily available for purchase, streamlining the research process and ensuring that scientists can focus on their experiments without the need for extensive preliminary cloning.
By choosing KMT5C Gene Knockout Cell Lines, researchers and clinicians alike benefit from a superior, focused tool that aids in uncovering the intricacies of gene function and epigenetic regulation. Our company specializes in providing high-quality genetic models and biological products, backed by a dedicated research team committed to delivering innovative solutions that advance scientific discovery and biotechnological applications.
Please note that all services are for research use only. Not intended for any clinical use.
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