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KLHL15 Knockout Cell Lines

Gene: KLHL15

Official Full Name: kelch like family member 15provided by HGNC

Gene Summary: This gene encodes a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-a-brac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. The encoded protein may be involved in protein ubiquitination and cytoskeletal organization. [provided by RefSeq, Apr 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26047 KLHL15 Knockout cell line (HeLa) Human KLHL15 1:3~1:6 Negative Online Inquiry
KO26048 KLHL15 Knockout cell line (HCT 116) Human KLHL15 1:2~1:4 Negative Online Inquiry
KO26049 KLHL15 Knockout cell line (HEK293) Human KLHL15 1:3~1:6 Negative Online Inquiry
KO26050 KLHL15 Knockout cell line (A549) Human KLHL15 1:3~1:4 Negative Online Inquiry

Background

KLHL15 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the KLHL15 gene’s role in various biological processes. These knockout models are created using advanced CRISPR-Cas9 technology, which precisely disrupts the gene's coding region, resulting in a complete loss of function. By eliminating KLHL15 expression, researchers can explore its involvement in critical pathways such as cellular stress responses, protein homeostasis, and developmental biology.

The key function of KLHL15 gene knockout cell lines revolves around their ability to unravel the cellular consequences of KLHL15 deficiency. Researchers can investigate alterations in cellular morphology, proliferation rates, and biochemical pathways, thereby gaining insights into the gene's regulatory functions and its impact on disease mechanisms. These cell lines are invaluable in clinical and research settings, particularly in the fields of oncology, neurobiology, and genetics, where understanding gene function is crucial for developing targeted therapies and interventions.

One of the major advantages of using KLHL15 gene knockout cell lines is the specificity and efficiency of the CRISPR-Cas9 technology, which significantly reduces off-target effects compared to older gene-editing techniques. Furthermore, these cell lines can be easily propagated and cultured, providing a reliable and reproducible experimental setup for high-throughput screening and functional assays.

Researchers and clinicians benefit from the KLHL15 gene knockout cell lines by obtaining a powerful tool for elucidating gene function and assessing the effects of gene manipulation. The insights garnered from these studies can hasten the development of novel diagnostic or therapeutic strategies tailored to diseases linked to KLHL15 dysregulation.

At [Your Company Name], we are committed to offering cutting-edge biological products that empower scientists and clinicians to make groundbreaking discoveries. Our expertise in gene-editing technologies ensures that our products, such as the KLHL15 Gene Knockout Cell Lines, meet the highest standards of quality and reliability, paving the way for transformative advancements in biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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