Gene: KLHL13
Official Full Name: kelch like family member 13provided by HGNC
Gene Summary: This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23805 | KLHL13 Knockout cell line (HeLa) | Human | KLHL13 | 1:3~1:6 | Negative | Online Inquiry |
KO23806 | KLHL13 Knockout cell line (HCT 116) | Human | KLHL13 | 1:2~1:4 | Negative | Online Inquiry |
KO23807 | KLHL13 Knockout cell line (HEK293) | Human | KLHL13 | 1:3~1:6 | Negative | Online Inquiry |
KO23808 | KLHL13 Knockout cell line (A549) | Human | KLHL13 | 1:3~1:4 | Negative | Online Inquiry |
KLHL13 Gene Knockout Cell Lines are advanced biological products created to facilitate the study of the KLHL13 gene, which is known to play a pivotal role in various cellular functions, including protein ubiquitination and cell signaling pathways. These cell lines are engineered to have a complete knockout of the KLHL13 gene, allowing researchers to investigate the gene's contribution to cellular processes and disease mechanisms with unparalleled precision.
The primary function of KLHL13 Gene Knockout Cell Lines lies in their ability to provide a controlled model for the investigation of gene function and the subsequent biological effects resulting from its absence. By utilizing CRISPR-Cas9 technology, these cell lines have been derived to ensure complete and specific deletion of the KLHL13 gene, enabling researchers to monitor changes in cellular behavior, gene expression profiles, and signaling pathways that may be affected as a consequence.
The scientific importance of these knockout cell lines cannot be overstated, as they serve as valuable tools in research areas such as oncology, neurobiology, and developmental biology. In clinical settings, understanding the role of KLHL13 can lead to insights into tumorigenesis and potential therapeutic targets. Their applications are broad, providing a pristine base for drug testing and validating potential interventions aimed at modulating KLHL13-related pathways.
One of the unique advantages of our KLHL13 Gene Knockout Cell Lines is their high specificity and efficiency. Unlike traditional knockout models, which may involve time-consuming screening and validation steps, our cell lines are ready-to-use and verified for gene disruption, allowing researchers to save time and resources. Additionally, these cell lines can be utilized in various assays, from gene expression analyses to drug screening, making them versatile tools in the laboratory.
For researchers and clinicians alike, the value of KLHL13 Gene Knockout Cell Lines lies in their ability to enhance understanding of gene function and its implications in health and disease. The detailed insights gained from using these models can pave the way for novel therapeutic strategies and the development of more effective treatments.
Our company prides itself on expertise in gene editing technologies and innovative biological product offerings. We are committed to providing high-quality research tools that assist scientists in their quest for knowledge and breakthroughs in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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