Gene: KIFC3
Official Full Name: kinesin family member C3provided by HGNC
Gene Summary: This gene encodes a member of the kinesin-14 family of microtubule motors. Members of this family play a role in the formation, maintenance and remodeling of the bipolar mitotic spindle. The protein encoded by this gene has cytoplasmic functions in the interphase cells. It may also be involved in the final stages of cytokinesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO36959 | KIFC3 Knockout cell line (HeLa) | Human | KIFC3 | 1:3~1:6 | Negative | Online Inquiry |
KO36960 | KIFC3 Knockout cell line (HCT 116) | Human | KIFC3 | 1:2~1:4 | Negative | Online Inquiry |
KO36961 | KIFC3 Knockout cell line (HEK293) | Human | KIFC3 | 1:3~1:6 | Negative | Online Inquiry |
KO36962 | KIFC3 Knockout cell line (A549) | Human | KIFC3 | 1:3~1:4 | Negative | Online Inquiry |
KIFC3 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study of the kinesin family of motor proteins, specifically Kinesin family member C3 (KIFC3). These cell lines have been generated through precise genomic editing techniques, effectively disrupting the KIFC3 gene, leading to the absence of functional KIFC3 protein. This knockout approach allows researchers to elucidate the role of KIFC3 in cellular processes such as mitosis, intracellular transport, and cell division.
The key mechanisms at work in KIFC3 Gene Knockout Cell Lines involve the use of CRISPR-Cas9 technology, which allows for targeted alterations within the genome. By knocking out the KIFC3 gene, researchers can investigate the downstream effects on cellular dynamics, particularly how the absence of this motor protein influences spindle formation, chromosome alignment, and transport dynamics within the cell. These investigations are crucial for understanding various physiological processes and the implications of KIFC3 dysfunction.
The scientific importance of KIFC3 Gene Knockout Cell Lines is particularly pronounced in cancer research and developmental biology. By exploring the functional consequences of KIFC3 absence, researchers can identify potential therapeutic targets for cancer treatment and gain insights into the mechanistic pathways that drive tumorigenesis. Additionally, these cell lines are invaluable for drug discovery and testing the efficacy of potential treatments aiming to modulate microtubule dynamics.
One significant advantage of KIFC3 Gene Knockout Cell Lines is their specificity. Unlike conventional cell lines that may exhibit variability, these knockout models provide consistent and reproducible results, reducing background noise in experimental data. Moreover, they are tailored for high-throughput screening initiatives, making them particularly advantageous for large-scale studies.
For researchers and clinicians, KIFC3 Gene Knockout Cell Lines represent a robust platform for advancing our understanding of motor protein functions, offering new pathways for investigation in both basic and applied biological research. Their unique capabilities enhance experimental design and promote discoveries that could lead to innovative therapeutic strategies.
Our company prides itself on extensive expertise in the field of genetic modification technologies, providing cutting-edge cell models that empower the scientific community. With a commitment to quality and innovation, we support researchers and clinicians in pushing the boundaries of biological understanding.
Please note that all services are for research use only. Not intended for any clinical use.
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