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KIF1A Knockout Cell Lines

Gene: KIF1A

Official Full Name: kinesin family member 1Aprovided by HGNC

Gene Summary: The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38870 KIF1A Knockout cell line (HEK293) Human KIF1A 1:3~1:6 Negative Online Inquiry

Background

KIF1A Gene Knockout Cell Lines are specialized biological tools designed to facilitate the study of the KIF1A gene, which encodes a motor protein crucial for intracellular transport along microtubules. By deploying CRISPR/Cas9 technology, these cell lines have been engineered to create precise gene knockouts, thereby allowing researchers to investigate the functional consequences of the gene's absence. This model is invaluable for understanding KIF1A's role in various physiological and pathological processes, including neuronal transport and associated neurodegenerative diseases.

The key mechanism behind the utility of KIF1A Gene Knockout Cell Lines lies in their ability to mimic disease conditions by disrupting KIF1A protein function. By analyzing these cell lines, scientists can elucidate the pathways affected by KIF1A loss and assess potential therapeutic targets. Furthermore, these cell lines provide a robust platform for high-throughput screening assays, facilitating drug discovery efforts aimed at ameliorating diseases linked to KIF1A dysfunction.

The scientific importance of KIF1A Gene Knockout Cell Lines is underscored by their diverse applications in both research and clinical settings. They are instrumental in neurobiology, developmental biology, and cancer research, allowing for the investigation of transport mechanisms critical for cell survival and function. Compared to traditional knockout models, these engineered cell lines offer greater efficiency, reproducibility, and specific control over gene expression, making them preferable for many researchers.

Investing in KIF1A Gene Knockout Cell Lines is essential for any laboratory focused on cutting-edge biological research. They not only accelerate discovery but also enhance the potential for innovative therapeutic strategies. Our company specializes in the development of high-quality biological research tools, backed by a team of experts committed to supporting scientists in their quest for knowledge and breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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