Gene: KCTD11
Official Full Name: potassium channel tetramerization domain containing 11provided by HGNC
Gene Summary: Enables identical protein binding activity. Predicted to be involved in positive regulation of neuron differentiation. Predicted to act upstream of or within negative regulation of neuroblast proliferation; negative regulation of smoothened signaling pathway; and neuron differentiation. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23868 | KCTD11 Knockout cell line (HeLa) | Human | KCTD11 | 1:3~1:6 | Negative | Online Inquiry |
KO23869 | KCTD11 Knockout cell line (HCT 116) | Human | KCTD11 | 1:2~1:4 | Negative | Online Inquiry |
KO23870 | KCTD11 Knockout cell line (HEK293) | Human | KCTD11 | 1:3~1:6 | Negative | Online Inquiry |
KO23871 | KCTD11 Knockout cell line (A549) | Human | KCTD11 | 1:3~1:4 | Negative | Online Inquiry |
KCTD11 Gene Knockout Cell Lines are specialized cell lines in which the KCTD11 gene has been deliberately inactivated to facilitate studies on gene function and related biological pathways. KCTD11, a member of the BTB-Kelch repeat protein family, is implicated in various cellular processes, including cell proliferation, differentiation, and apoptosis. By creating knockout variants of this gene, researchers can investigate the specific roles that KCTD11 plays within both normal physiological contexts and disease states.
The primary mechanism behind these gene knockout cell lines involves CRISPR/Cas9 technology, a revolutionary genome editing tool that allows for highly precise modifications to DNA. This technique enables the specific targeting and disruption of the KCTD11 gene, leading to its functional absence within the cell lines. This cellular model is invaluable for researchers in delineating molecular mechanisms, as well as for screening potential therapeutic interventions against disorders linked to KCTD11 dysregulation, such as certain cancers and neurodevelopmental disorders.
Scientifically, KCTD11 Gene Knockout Cell Lines offer numerous applications, including gene expression studies, cellular response assays, and drug discovery platforms. They uniquely allow for the examination of KCTD11's functional role and its interactions with other biomolecules within the cellular milieu. Compared to traditional methods such as RNA interference, the knockout approach provides a more enduring and complete loss of gene function, facilitating thorough investigation of the gene's impact.
Researchers and clinicians will find these cell lines especially valuable for advancing knowledge in areas such as molecular biology, pharmacology, and genetics. By deploying KCTD11 Gene Knockout Cell Lines, users can unlock new insights into therapeutic targets, enabling the development of innovative treatment strategies.
As a company committed to providing high-quality, precision biological products, we leverage advanced genomic technologies and a robust understanding of molecular biology to offer outstanding tools for the scientific community. Our KCTD11 Gene Knockout Cell Lines are not just tools—they're essential components in the pursuit of groundbreaking discoveries and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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