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KATNAL1 Knockout Cell Lines

Gene: KATNAL1

Official Full Name: katanin catalytic subunit A1 like 1provided by HGNC

Gene Summary: Enables identical protein binding activity and microtubule severing ATPase activity. Involved in microtubule severing. Located in cytoplasm; microtubule; and spindle pole. Part of katanin complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25257 KATNAL1 Knockout cell line (HeLa) Human KATNAL1 1:3~1:6 Negative Online Inquiry
KO25258 KATNAL1 Knockout cell line (HCT 116) Human KATNAL1 1:2~1:4 Negative Online Inquiry
KO25259 KATNAL1 Knockout cell line (HEK293) Human KATNAL1 1:3~1:6 Negative Online Inquiry
KO25260 KATNAL1 Knockout cell line (A549) Human KATNAL1 1:3~1:4 Negative Online Inquiry

Background

KATNAL1 Gene Knockout Cell Lines are essential experimental tools utilized in cell biology, genetics, and related fields to study the functions and regulation of the KATNAL1 gene. By employing CRISPR/Cas9 technology, these cell lines have been specifically engineered to disrupt the expression of the KATNAL1 gene, resulting in an informative model to investigate its role in cellular processes such as microtubule dynamics and neuronal function.

The key function of KATNAL1 is its involvement in the stabilization and regulation of microtubules, which are essential for proper intracellular transport, cell division, and maintaining the structural integrity of cells. By utilizing these knockout cell lines, researchers can explore the consequences of KATNAL1 depletion on cellular behavior, signaling pathways, and the interaction between microtubules and other cellular components. This knowledge is particularly important in the context of neurodegenerative diseases and developmental disorders, where microtubule dysfunction is often implicated.

In terms of scientific importance, KATNAL1 Gene Knockout Cell Lines offer application potential in both research and clinical settings. They enable the elucidation of molecular mechanisms underlying various pathological states and provide a platform for drug testing and the development of novel therapeutic strategies targeting microtubule-associated pathologies.

One of the most notable advantages of these cell lines lies in their specificity and reliability. Unlike other available models that may exhibit off-target effects or incomplete gene disruption, our KATNAL1 knockout cell lines ensure robust and reproducible results, helping researchers to draw meaningful conclusions without the confounding factors introduced by inadequate genetic models.

For researchers and clinicians invested in understanding the cellular role of KATNAL1, these cell lines represent a valuable resource to advance their studies in genetics and disease mechanisms. Our company brings extensive expertise in generating reliable biological tools, ensuring that each product meets high standards of quality and usability, facilitating innovative research towards the betterment of human health.

Please note that all services are for research use only. Not intended for any clinical use.

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