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KAT5 Knockout Cell Lines

Gene: KAT5

Official Full Name: lysine acetyltransferase 5provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00599 KAT5 Knockout cell line (HeLa) Human KAT5 1:3~1:6 Negative Online Inquiry

Background

KAT5 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to have the KAT5 gene (also known as Tip60) disrupted or knocked out. KAT5 plays a critical role in various biological processes, such as DNA repair, histone modification, and the regulation of p53, making these knockout lines invaluable for understanding its functional significance. By eliminating the KAT5 gene, these cell lines allow researchers to assess the consequences of its absence on cellular pathways, gene expression, and overall cellular behavior.

The primary mechanism of action in KAT5 knockout cell lines lies in their ability to mimic specific disease states or cellular dysfunctions. By studying these cell lines, scientists can uncover the implications of KAT5 loss on cellular proliferation, apoptosis, and response to DNA-damaging agents, aiding in the elucidation of cancerogenesis and other pathological conditions where KAT5 is implicated. This makes them highly relevant for both academic research and pharmaceutical applications, particularly in cancer biology, drug development, and cellular signaling studies.

Compared to traditional wild-type cell lines, KAT5 knockout cell lines provide a unique vantage point for investigating gene function. Their specificity drastically reduces background noise and allows for more accurate hypothesis testing, leading to more relevant and repeatable experimental results. By offering these knockout models, researchers are equipped with powerful tools that can significantly streamline the discovery process for novel therapeutic targets and biomarkers.

For scientists and clinicians, the value of utilizing KAT5 Gene Knockout Cell Lines lies in their capability to enhance the understanding of KAT5's role in disease mechanics and facilitate the development of targeted therapies. They provide a controlled environment that promotes reproducibility and accessibility, ultimately leading to faster advancements in research outcomes.

With a commitment to innovation and quality, our company specializes in delivering high-caliber biological products, tailored to meet the needs of researchers and clinicians seeking to advance their scientific inquiries. Our expertise guarantees that you receive reliable, well-characterized cell lines that are essential for cutting-edge research in molecular and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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