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JHY Knockout Cell Lines

Gene: JHY

Official Full Name: junctional cadherin complex regulatorprovided by HGNC

Gene Summary: Predicted to be involved in axoneme assembly and brain development. Predicted to act upstream of or within several processes, including cerebrospinal fluid circulation; motile cilium assembly; and regulation of establishment of planar polarity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16854 JHY Knockout cell line (HeLa) Human JHY 1:3~1:6 Negative Online Inquiry
KO16855 JHY Knockout cell line (HCT 116) Human JHY 1:2~1:4 Negative Online Inquiry
KO16856 JHY Knockout cell line (HEK293) Human JHY 1:3~1:6 Negative Online Inquiry
KO16857 JHY Knockout cell line (A549) Human JHY 1:3~1:4 Negative Online Inquiry

Background

JHY Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of specific gene functions through the targeted disruption of those genes. This product is constructed using advanced CRISPR-Cas9 technology, which allows for precise editing of the genomic sequence to deactivate or "knock out" the gene of interest. By enabling researchers to create cellular systems that lack specific genes, JHY Gene Knockout Cell Lines serve as powerful tools for elucidating the roles of those genes in various biological processes.

One of the key functions of the JHY Gene Knockout Cell Lines is their ability to mimic disease states by removing critical signaling pathways or metabolic functions attributed to specific genes. This process provides insights into gene function in relation to cellular behavior, drug responses, and interaction with other biological molecules. Additionally, these cell lines are invaluable for the development and testing of gene therapies, as they help elucidate the mechanisms underlying genetic disorders.

The scientific importance of JHY Gene Knockout Cell Lines extends into both basic and applied research settings. They are crucial for studying gene function in areas such as oncology, developmental biology, and neurobiology, thereby accelerating drug discovery and improving the understanding of disease mechanisms. In clinical research, they enable researchers to evaluate the therapeutic potential of new treatments against genetically characterized disease models, leading to more effective intervention strategies.

The advantages of JHY Gene Knockout Cell Lines lie in their reliability, consistency, and high efficiency of gene editing, offering a more straightforward solution compared to traditional methods like siRNA or shRNA approaches. With a diverse range of gene targets available, researchers can easily customize their models, which differs significantly from existing commercial options that may not provide the same level of specificity or ease of use.

For researchers and clinicians, the value of JHY Gene Knockout Cell Lines is further underscored by their robust performance in experimental reproducibility and their ability to significantly accelerate research timelines. They serve as a critical resource for advancing our understanding of genetics and developing novel therapeutic interventions.

Our company prides itself on its deep expertise in producing high-quality biological products, ensuring that our JHY Gene Knockout Cell Lines meet the rigorous standards demanded by the scientific community. With a commitment to innovation and support for our customers, we strive to empower researchers in their quest for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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