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ISM1 Knockout Cell Lines

Gene: ISM1

Official Full Name: isthmin 1provided by HGNC

Gene Summary: Predicted to be involved in negative regulation of angiogenesis. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25528 ISM1 Knockout cell line (HCT 116) Human ISM1 1:2~1:4 Negative Online Inquiry
KO25529 ISM1 Knockout cell line (HEK293) Human ISM1 1:3~1:6 Negative Online Inquiry

Background

ISM1 Gene Knockout Cell Lines are advanced laboratory tools specifically engineered to study the biological functions of the ISM1 gene by providing a cellular model devoid of its expression. These cell lines have been constructed using cutting-edge CRISPR-Cas9 gene-editing technology, which enables precise and efficient genomic modifications. By permanently knocking out the ISM1 gene, these models allow researchers to investigate the gene's role in various cellular processes, disease mechanisms, and potential therapeutic pathways.

The primary function of ISM1 Gene Knockout Cell Lines lies in their utility for gene function studies, including investigations into cellular differentiation, proliferation, and apoptosis. Mechanistically, the absence of ISM1 alters signaling pathways that are crucial for gene expression regulation, offering an unparalleled opportunity to observe the downstream effects of its knockout in controlled experimental conditions. This makes it an invaluable resource for both basic research and drug development.

The scientific importance of ISM1 Gene Knockout Cell Lines cannot be overstated, as they facilitate insights into the gene's contributions in both normal physiology and disease states, such as cancer or neurological disorders. This provides crucial data that could inform the design of targeted therapeutic interventions, ultimately leading to novel treatment options in clinical practice.

Compared to other gene knockout systems which may have off-target effects or inadequate expression control, our ISM1 Gene Knockout Cell Lines offer enhanced precision and reproducibility, thereby increasing the reliability of experimental outcomes. Additionally, our cell lines come with comprehensive technical support and documentation, ensuring that researchers can easily integrate them into their existing work.

For researchers and clinicians exploring the functional aspects of the ISM1 gene, these cell lines are indispensable. They not only advance the understanding of gene function but also lay the groundwork for innovative therapeutic strategies.

Our company, with years of experience in biotechnological innovations, is committed to providing high-quality biological products. We pride ourselves on enabling scientific excellence and empowering researchers with the tools necessary to push the boundaries of biological discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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