Gene: INSYN1
Official Full Name: inhibitory synaptic factor 1provided by HGNC
Gene Summary: Predicted to be involved in inhibitory postsynaptic potential. Predicted to be located in synapse. Predicted to be active in GABA-ergic synapse and postsynaptic density. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16909 | INSYN1 Knockout cell line (HCT 116) | Human | INSYN1 | 1:2~1:4 | Negative | Online Inquiry |
KO16910 | INSYN1 Knockout cell line (HEK293) | Human | INSYN1 | 1:3~1:6 | Negative | Online Inquiry |
KO16911 | INSYN1 Knockout cell line (A549) | Human | INSYN1 | 1:3~1:4 | Negative | Online Inquiry |
INSYN1 Gene Knockout Cell Lines are specifically engineered mammalian cell lines that have been genetically modified to disrupt the INSYN1 gene, a critical component in various cellular processes. These cell lines serve as an invaluable resource for researchers investigating gene function, signal transduction pathways, and the implications of INSYN1 deficiency in disease models. By employing targeted CRISPR/Cas9 technology, INSYN1 Gene Knockout Cell Lines provide a robust platform for studying gene function in both physiological and pathological contexts.
The primary function of these cell lines lies in their ability to elucidate the role of the INSYN1 gene in neurotransmitter release and synaptic plasticity. By knocking out this gene, researchers can observe resultant phenotypic changes at both cellular and molecular levels, offering insights into neurodevelopmental disorders and various neurodegenerative diseases. Through careful analysis of these alterations, scientists can generate valuable data that informs drug design and therapeutic interventions.
Scientific significance is paramount as INSYN1 has been implicated in critical pathways associated with synaptic function and neuronal communication, making these knockout cell lines a vital tool for advancing our understanding of neural connectivity and plasticity. Their application extends to both basic research and clinical settings, where they facilitate the development of new therapeutic strategies or elucidate mechanisms underlying existing conditions.
What sets INSYN1 Gene Knockout Cell Lines apart from traditional models is their precision and reliability. Unlike other knockouts that may yield off-target effects or inconsistent results, these cell lines provide a consistent and reproducible environment for experimentation, thus enhancing the reliability of research findings. Additionally, their versatility allows for use in various applications, from high-throughput screening to collaborative research in pharmacology and genetics.
For researchers and clinicians alike, the value of INSYN1 Gene Knockout Cell Lines cannot be overstated. They not only streamline experimental workflows but also contribute to groundbreaking discoveries in the field of neuroscience. Our company is dedicated to providing high-quality biological products with a focus on innovation and rigorous scientific validation, ensuring that our clients have access to advanced tools necessary for their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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