Gene: IGSF9B
Official Full Name: immunoglobulin superfamily member 9Bprovided by HGNC
Gene Summary: Predicted to enable kinase binding activity. Predicted to be involved in synaptic membrane adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules and positive regulation of inhibitory postsynaptic potential. Predicted to be located in dendrite; inhibitory synapse; and neuronal cell body. Predicted to be active in GABA-ergic synapse; neuron projection; and postsynaptic specialization of symmetric synapse. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30045 | IGSF9B Knockout cell line (HCT 116) | Human | IGSF9B | 1:2~1:4 | Negative | Online Inquiry |
KO30046 | IGSF9B Knockout cell line (HEK293) | Human | IGSF9B | 1:3~1:6 | Negative | Online Inquiry |
IGSF9B Gene Knockout Cell Lines are specialized cellular models engineered to lack the IGSF9B gene, which is implicated in a variety of biological processes including cell adhesion, signaling pathways, and neural development. These knockout cell lines are created using advanced gene editing technologies, such as CRISPR-Cas9, allowing for the specific and permanent disruption of the IGSF9B gene, enabling researchers to investigate its functions and interactions in detail.
The primary function of IGSF9B encompasses roles in synaptic differentiation and adhesion, which are vital for neuronal connectivity and function. By utilizing these knockout cell lines, scientists can explore how the absence of IGSF9B affects cellular behavior, signaling pathways, and gene expression patterns. This understanding aids in deciphering the genetic contributions to neurological disorders and related pathologies, facilitating the discovery of potential therapeutic targets.
The scientific significance of IGSF9B Gene Knockout Cell Lines extends to both basic research and clinical applications. In research settings, they serve as valuable tools for elucidating the role of IGSF9B in neural tissue and its influence on neurodevelopmental processes. Clinically, insights gained from these studies can inform strategies for treating conditions linked to IGSF9B dysfunction, including neurodevelopmental disorders and cognitive impairments.
One of the standout advantages of IGSF9B Gene Knockout Cell Lines is their specificity and reliability. Unlike other methods that may employ temporary knockdown techniques leading to inconsistent results, these knockout lines provide a stable and permanent genetic alteration, ensuring reproducibility in experimental outcomes. Furthermore, the precision of the CRISPR genome-editing technique minimizes off-target effects, thereby enhancing the credibility of research findings.
For researchers, clinicians, and industry professionals, IGSF9B Gene Knockout Cell Lines represent an invaluable resource for advancing our knowledge of cellular and molecular mechanisms governing neurological function. They empower scientists to perform targeted investigations with high confidence and reproducibility.
Our company is dedicated to providing innovative biological products backed by extensive expertise in genetic engineering, ensuring that scientists have access to the highest quality cell lines for their groundbreaking research.
Please note that all services are for research use only. Not intended for any clinical use.
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