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IGFLR1 Knockout Cell Lines

Gene: IGFLR1

Official Full Name: IGF like family receptor 1provided by HGNC

Gene Summary: Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16978 IGFLR1 Knockout cell line (HeLa) Human IGFLR1 1:3~1:6 Negative Online Inquiry
KO16979 IGFLR1 Knockout cell line (HCT 116) Human IGFLR1 1:2~1:4 Negative Online Inquiry
KO16980 IGFLR1 Knockout cell line (HEK293) Human IGFLR1 1:3~1:6 Negative Online Inquiry
KO16981 IGFLR1 Knockout cell line (A549) Human IGFLR1 1:3~1:4 Negative Online Inquiry

Background

IGFLR1 Gene Knockout Cell Lines are specialized cell lines engineered to provide a complete knockout of the Insulin-like Growth Factor-Like Receptor 1 (IGFLR1) gene. This innovative product is designed to facilitate research into the role of IGFLR1 in cellular processes such as growth, differentiation, and survival. By disrupting the expression of IGFLR1, these cell lines enable scientists to investigate the receptor's contributions to various biological pathways and disease states, particularly in oncology and metabolic disorders.

The mechanisms that underpin the functionality of IGFLR1 Gene Knockout Cell Lines involve CRISPR-Cas9 technology, a cutting-edge gene-editing tool that precisely alters DNA sequences. The knockout process results in the generation of a stable cell population devoid of IGFLR1 expression, allowing researchers to conduct comparative analyses against wild-type control cells. This allows for a clearer understanding of IGFLR1's role in signaling pathways and further elucidates its involvement in tumorigenesis and metabolic regulation.

The scientific importance of this product lies in its versatile applications across both research and clinical settings. Researchers can utilize these cell lines to model diseases, conduct drug discovery studies, and develop targeted therapies. The absence of IGFLR1 provides a unique platform for assessing potential therapeutic targets related to IGF pathways and understanding resistance mechanisms in cancer treatments.

Among the alternatives in the market, IGFLR1 Gene Knockout Cell Lines stand out due to their robustness and the precision of gene editing. These knockout models allow for reproducible results, minimizing variability seen in other cell models, such as those derived from spontaneous mutations or transfection methods.

For researchers, clinicians, and pharmaceutical developers dedicated to advancing the understanding of IGF signaling and its broader implications in human health, IGFLR1 Gene Knockout Cell Lines represent an invaluable tool. This product not only accelerates the pace of discovery but also enhances the accuracy of experimental outcomes.

Our company is committed to providing high-quality biological products supported by extensive expertise in genetic engineering, ensuring that researchers have access to reliable and effective tools to facilitate breakthroughs in their work.

Please note that all services are for research use only. Not intended for any clinical use.

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