Gene: IFRD1
Official Full Name: interferon related developmental regulator 1provided by HGNC
Gene Summary: This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02769 | IFRD1 Knockout cell line (HeLa) | Human | IFRD1 | 1:3~1:6 | Negative | Online Inquiry |
KO02770 | IFRD1 Knockout cell line (HCT 116) | Human | IFRD1 | 1:2~1:4 | Negative | Online Inquiry |
KO02771 | IFRD1 Knockout cell line (HEK293) | Human | IFRD1 | 1:3~1:6 | Negative | Online Inquiry |
KO02772 | IFRD1 Knockout cell line (A549) | Human | IFRD1 | 1:3~1:4 | Negative | Online Inquiry |
IFRD1 Gene Knockout Cell Lines are specialized cellular models engineered to entirely disable the expression of the IFRD1 gene, which encodes Interferon-related developmental regulator 1. Through state-of-the-art CRISPR-Cas9 gene-editing techniques, these cell lines exhibit highly efficient and specific knockouts, enabling researchers to investigate the role of IFRD1 in various biological processes and disease states.
The key function of the IFRD1 Gene Knockout Cell Lines lies in their ability to mimic the phenotypic and functional consequences of IFRD1 deficiency. This gene has been implicated in immune responses, cell proliferation, and differentiation; thus, knockout models enable in-depth studies into how these mechanisms are altered in conditions such as cancer, autoimmune disorders, and infectious diseases. By providing a system to assess aberrant cellular behaviors and signaling pathways, these cell lines serve as potent tools in elucidating the biological relevance of IFRD1 in both basic and translational research.
Scientifically, the application of IFRD1 Knockout Cell Lines holds significant promise in biomedical research and clinical drug development. They allow for the identification of potential therapeutics targeting IFRD1-related pathways, thereby paving the way for new treatment strategies. Their distinct use in functional assays and high-throughput screenings ensures researchers can draw reliable correlations between IFRD1 activity and disease progression.
In comparison to traditional models that utilize overexpression or silencing techniques, the use of IFRD1 Gene Knockout Cell Lines offers several advantages. These knockout cells ensure a complete absence of the target gene, providing a clearer understanding of its role without the confounding effects of residual activity. Additionally, the reproducibility and stability of knockout lines enhance experimental reliability, reducing variability.
Researchers and clinicians looking for robust and validated cellular models will find our IFRD1 Gene Knockout Cell Lines invaluable for advancing their studies and therapeutic endeavors. Our company's commitment to excellence in genetic engineering and our extensive product offerings in gene-editing technologies underscore our dedication to supporting breakthrough discoveries in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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