Gene: IFIT5
Official Full Name: interferon induced protein with tetratricopeptide repeats 5provided by HGNC
Gene Summary: Enables nucleic acid binding activity. Involved in defense response to virus; negative regulation of viral genome replication; and positive regulation of canonical NF-kappaB signal transduction. Located in several cellular components, including IkappaB kinase complex; actin cytoskeleton; and ruffle membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28932 | IFIT5 Knockout cell line (HeLa) | Human | IFIT5 | 1:3~1:6 | Negative | Online Inquiry |
KO28933 | IFIT5 Knockout cell line (HCT 116) | Human | IFIT5 | 1:2~1:4 | Negative | Online Inquiry |
KO28934 | IFIT5 Knockout cell line (HEK293) | Human | IFIT5 | 1:3~1:6 | Negative | Online Inquiry |
KO28935 | IFIT5 Knockout cell line (A549) | Human | IFIT5 | 1:3~1:4 | Negative | Online Inquiry |
IFIT5 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the Interferon-Induced Protein With Tetratricopeptide Repeats 5 (IFIT5) gene. These cell lines are invaluable tools for researchers aiming to study the functional role of IFIT5 in various biological processes, particularly in the context of antiviral responses, cellular stress mechanisms, and tumor biology.
The key functionality of IFIT5 Gene Knockout Cell Lines is rooted in their ability to mimic physiological conditions devoid of the IFIT5 protein, allowing researchers to investigate its influence on cellular pathways. By utilizing CRISPR/Cas9 techniques, these lines demonstrate precise gene editing, ensuring a complete and consistent knockout of IFIT5. This capability enables scientists to explore how the absence of IFIT5 affects cell signaling in response to viral infections, making these cell lines essential for virology research, immunological studies, and the development of targeted therapies.
Scientifically, IFIT5 Gene Knockout Cell Lines hold significant importance in basic and applied research. Their application extends to drug screening, gene therapy development, and understanding resistance mechanisms in cancer therapy. Moreover, their use can facilitate the identification of novel biomarkers for diseases linked with IFIT5 dysregulation, thereby enhancing the translational potential of research findings into clinical settings.
What sets our IFIT5 Gene Knockout Cell Lines apart from other available models is the rigorous validation process undertaken to ensure stability, functionality, and reproducibility. Each batch undergoes comprehensive characterization, guaranteeing that researchers receive a high-quality product that meets their experimental needs. Additionally, our commitment to providing detailed technical support helps researchers maximize the utility of these cell lines, streamlining their experimental workflows.
For researchers, clinicians, and biopharmaceutical companies, our IFIT5 Gene Knockout Cell Lines offer an unparalleled advantage in elucidating the multifaceted roles of the IFIT5 protein. By choosing our product, users gain confidence in their research outcomes, which can potentially lead to groundbreaking discoveries and effective therapeutic strategies.
With extensive expertise in developing advanced biological products, our company stands as a leader in the field, dedicated to supporting scientific innovation and improving outcomes across diverse research and clinical arenas.
Please note that all services are for research use only. Not intended for any clinical use.
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