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HPDL Knockout Cell Lines

Gene: HPDL

Official Full Name: 4-hydroxyphenylpyruvate dioxygenase likeprovided by HGNC

Gene Summary: The protein encoded by this intronless gene localizes to mitochondria, where it may function as 4-hydroxyphenylpyruvate dioxygenase. Clinical studies have identified several bi-allelic variants in this gene that lower the level of the encoded protein and lead to a clinically variable form of pediatric-onset spastic movement disorder. [provided by RefSeq, Aug 2020]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07327 HPDL Knockout cell line (HeLa) Human HPDL 1:3~1:6 Negative Online Inquiry
KO07328 HPDL Knockout cell line (A549) Human HPDL 1:3~1:4 Negative Online Inquiry

Background

HPDL Gene Knockout Cell Lines are genetically engineered cells in which the HPDL gene has been selectively inactivated to facilitate advanced research into gene function and related biological processes. This innovative approach allows scientists to investigate the role of the HPDL gene in various cellular functions, signaling pathways, and disease mechanisms, providing insights that are crucial for the development of targeted therapies.

The key function of HPDL Gene Knockout Cell Lines is to enable the study of phenotypic changes resulting from the absence of the HPDL gene. By utilizing CRISPR/Cas9 technology or other gene-editing methods, researchers can achieve a precise knockout of the gene and investigate its impact on cellular behaviors such as proliferation, apoptosis, and response to environmental stimuli. These cell lines serve as powerful tools for elucidating molecular pathways and exploring potential genetic interactions, thereby broadening our understanding of pathology associated with HPDL dysregulation.

In both basic and applied biomedical research, the HPDL Gene Knockout Cell Lines have significant implications. They are invaluable for drug discovery, as they allow for the assessment of therapeutic compounds in a genetically modified context. Moreover, they can aid in identifying biomarker candidates for precision medicine, as altered expression levels could correlate with specific disease states.

The unique selling point of HPDL Gene Knockout Cell Lines lies in their specificity and the precision of gene editing, which surpasses more traditional methods such as siRNA knockdown that may yield transient effects. Our cell lines provide stable and reproducible knockout models essential for deeper investigations into gene function, making them indispensable for researchers looking to achieve rigorous results.

For researchers and clinicians, the HPDL Gene Knockout Cell Lines offer not just biological insights but also a strategic advantage in the competitive fields of gene therapy and translational research. With our expertise in developing high-quality biological products, we are committed to supporting scientific inquiries that will lead to transformative breakthroughs in health and disease management.

Please note that all services are for research use only. Not intended for any clinical use.

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