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HORMAD1 Knockout Cell Lines

Gene: HORMAD1

Official Full Name: HORMA domain containing 1provided by HGNC

Gene Summary: This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25232 HORMAD1 Knockout cell line (HeLa) Human HORMAD1 1:3~1:6 Negative Online Inquiry
KO25233 HORMAD1 Knockout cell line (A549) Human HORMAD1 1:3~1:4 Negative Online Inquiry

Background

HORMAD1 Gene Knockout Cell Lines are genetically engineered cell lines that lack the expression of the HORMAD1 gene, which plays a critical role in the DNA damage response and meiotic processes. This product serves as an invaluable tool for researchers investigating the molecular mechanisms of genomic stability, meiosis, and the associated pathways involved in cellular responses to DNA damage. By utilizing these knockout cell lines, scientists can study the downstream effects of HORMAD1 deficiency, gain insights into the processes of homologous recombination, and examine how alterations in HORMAD1 expression can influence various disease states, particularly infertility and cancer.

The key mechanism of HORMAD1 involves its function in the formation of the synaptonemal complex during meiosis and its interaction with multiple proteins involved in DNA repair pathways. By effectively knocking out this gene, researchers can delineate the role of HORMAD1 in homologous recombination and identify compensatory mechanisms that cells may utilize in response to its absence. This loss of function allows for a deeper understanding of the regulatory networks that underpin cell cycle progression and genomic integrity.

In terms of scientific importance, these knockout cell lines are particularly useful for foundational research and drug discovery. They facilitate investigations into novel therapeutic targets related to diseases caused by defects in mating-type genes, such as certain types of cancer that exhibit genomic instability. Compared to other alternatives, HORMAD1 Gene Knockout Cell Lines provide a highly specific approach, allowing for controlled studies without confounding results from partial gene expression or activity.

What sets our product apart is not only its superior specificity and reliability but also its ease of use in various cellular assays. Researchers can rely on our HORMAD1 knockout cell lines to generate reproducible and meaningful data, significantly enhancing the quality of their research outputs.

Our company prides itself on its cutting-edge biotechnological solutions and expertise in developing high-quality genetic models that accelerate scientific discovery. By choosing HORMAD1 Gene Knockout Cell Lines, you're selecting a trusted partner in advancing your research towards new insights and breakthroughs in biological sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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