Gene: HNRNPR
Official Full Name: heterogeneous nuclear ribonucleoprotein Rprovided by HGNC
Gene Summary: This gene encodes an RNA-binding protein that is a member of the spliceosome C complex, which functions in pre-mRNA processing and transport. The encoded protein also promotes transcription at the c-fos gene. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes 4, 11, and 10. [provided by RefSeq, Jul 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32093 | HNRNPR Knockout cell line (HeLa) | Human | HNRNPR | 1:3~1:6 | Negative | Online Inquiry |
KO32094 | HNRNPR Knockout cell line (HCT 116) | Human | HNRNPR | 1:2~1:4 | Negative | Online Inquiry |
KO32095 | HNRNPR Knockout cell line (HEK293) | Human | HNRNPR | 1:3~1:6 | Negative | Online Inquiry |
KO32096 | HNRNPR Knockout cell line (A549) | Human | HNRNPR | 1:3~1:4 | Negative | Online Inquiry |
HNRNPR Gene Knockout Cell Lines are specifically engineered cellular models designed to investigate the function of the heterogeneous nuclear ribonucleoprotein R (HNRNPR) gene by selectively silencing its expression. These cell lines utilize robust gene-editing techniques, such as CRISPR-Cas9, to ensure precise gene knockout. With the disruption of HNRNPR, researchers can observe the resulting phenotypic changes and elucidate the roles this protein plays in mRNA processing, cellular signaling pathways, and stress response mechanisms.
The primary function of HNRNPR is to participate in diverse aspects of RNA metabolism, including splicing, transport, and translation regulation. By studying these knockout cell lines, scientists can gain insights into the molecular underpinnings of various diseases, including cancer and neurodegenerative disorders, where aberrations in RNA processing are commonly observed. The ability to observe these alterations in a controlled environment enhances our understanding of HNRNPR's biological roles.
This product holds significant scientific importance in both research and clinical settings, offering a platform for drug discovery, mechanism of action studies, and therapeutic target validation. Unlike conventional models that may not accurately reflect the multifactorial nature of gene function, HNRNPR Gene Knockout Cell Lines provide a streamlined and relevant system for answering critical biological questions.
Unique selling points include the high efficiency of gene knockout, ease of use in various experimental setups, and comprehensive support data that assists in replicating experiments. Additionally, comparing alternative approaches, these cell lines provide a more accurate simulation of the human physiological environment.
For researchers and clinicians aiming to expand their investigations into gene function and disease pathology, the HNRNPR Gene Knockout Cell Lines represent a valuable resource. They empower scientists to conduct translatable research that can lead to understanding disease mechanisms and potential therapeutic interventions.
Our company is committed to providing superior biological products and resources, underpinned by extensive expertise in gene editing technologies. With a focus on innovation and quality, we ensure that our offerings, including HNRNPR Gene Knockout Cell Lines, meet the highest scientific standards for today's research demands.
Please note that all services are for research use only. Not intended for any clinical use.
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