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HACD1 Knockout Cell Lines

Gene: HACD1

Official Full Name: 3-hydroxyacyl-CoA dehydratase 1provided by HGNC

Gene Summary: The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33478 HACD1 Knockout cell line (HeLa) Human HACD1 1:3~1:6 Negative Online Inquiry
KO33479 HACD1 Knockout cell line (HCT 116) Human HACD1 1:2~1:4 Negative Online Inquiry
KO33480 HACD1 Knockout cell line (HEK293) Human HACD1 1:3~1:6 Negative Online Inquiry
KO33481 HACD1 Knockout cell line (A549) Human HACD1 1:3~1:4 Negative Online Inquiry

Background

HACD1 Gene Knockout Cell Lines represent a significant advancement in cellular biology, specifically designed to facilitate the study of the HACD1 gene's function and its role in various biological processes. These cell lines have been genetically engineered to induce a complete knockout of the HACD1 gene, thereby allowing researchers to observe the phenotypic and molecular changes that occur in the absence of this specific gene, which is crucial for the synthesis of certain types of lipids and cellular architecture.

The key mechanism through which these knockout cell lines operate involves the targeted disruption of the HACD1 genomic sequence, using methods such as CRISPR-Cas9 technology. This precision editing enables an in-depth analysis of gene function, protein interactions, and downstream signaling pathways, providing researchers a powerful tool to dissect the complexities of lipogenesis and associated metabolic disorders.

Scientifically, HACD1 is increasingly recognized for its potential involvement in various conditions, including metabolic syndromes and neurodegenerative diseases. The ability to study its knockout variants allows for deeper insights into these diseases, making the cell lines invaluable in translational research and drug discovery applications.

One of the unique selling points of HACD1 Gene Knockout Cell Lines is their high fidelity and reproducibility. Unlike traditional cell lines, these knockout models provide a clean background that eliminates confounding variables, allowing for more reliable experimental outcomes. Additionally, they can be cultured under standard laboratory conditions, making them accessible for widespread use in both academic and pharmaceutical research settings.

For researchers and clinicians focused on lipid metabolism and its implications in health and disease, these cell lines offer an unparalleled opportunity to generate novel insights and develop targeted therapeutic strategies. By utilizing HACD1 Gene Knockout Cell Lines, users can engage in cutting-edge research that could contribute significantly to the understanding and treatment of various metabolic disorders.

Our company specializes in providing high-quality, genetically engineered cell lines, designed with precision and backed by extensive technical support. We are committed to advancing scientific inquiry and fostering innovation in biological research, ensuring that our customers have access to the most effective tools available.

Please note that all services are for research use only. Not intended for any clinical use.

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