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H4C2 Knockout Cell Lines

Gene: H4C2

Official Full Name: H4 clustered histone 2provided by HGNC

Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34221 H4C2 Knockout cell line (HEK293) Human H4C2 1:3~1:6 Negative Online Inquiry

Background

H4C2 Gene Knockout Cell Lines are specialized human cell lines that have been genetically engineered to exhibit targeted deletions of specific genes associated with various biological processes and diseases. This innovative approach allows researchers to study gene function and regulation in a controlled environment, making H4C2 cell lines critical tools for understanding the molecular mechanisms underlying cell behavior, disease pathology, and potential therapeutic interventions.

The functionality of H4C2 Gene Knockout Cell Lines is rooted in the precise gene-editing techniques employed, such as CRISPR-Cas9 or RNA interference, which enable the selective knockout of specific target genes. This mechanism facilitates the investigation of gene roles in cellular processes including metabolism, signal transduction, and apoptosis. By analyzing the morphological, biochemical, and molecular changes that occur following gene disruption, researchers can glean insights into various biological pathways and identify new therapeutic targets.

The scientific importance of H4C2 Gene Knockout Cell Lines is evident in both fundamental research and clinical applications. In academic settings, these cell lines provide invaluable models for studying gene function in processes such as cancer biology, neurodegeneration, and metabolic disorders. Furthermore, in a clinical context, the data gleaned from these knockouts can inform the development of targeted therapies and precision medicine approaches.

Compared to traditional cell culture models, H4C2 Gene Knockout Cell Lines offer distinct advantages, including the ability to replicate in vivo gene expression patterns more accurately and their capacity to provide insights into gene interdependencies. Their specificity and precision enable researchers to generate high-quality, reproducible data that can lead to breakthroughs in understanding human diseases.

For researchers and clinicians seeking to provide the best possible solutions in their studies and treatments, H4C2 Gene Knockout Cell Lines stand out as essential tools with high relevance in current biomedical research. Our company prides itself on delivering advanced and reliable biological products, grounded in a commitment to scientific excellence and dedicated customer support. With a team of experts in genetic engineering and cell biology, we continue to innovate and expand our offerings to meet the diverse needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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