Gene: H4C16
Official Full Name: H4 histone 16provided by HGNC
Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Aug 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17182 | H4C16 Knockout cell line (HeLa) | Human | H4C16 | 1:3~1:6 | Negative | Online Inquiry |
KO17183 | H4C16 Knockout cell line (HCT 116) | Human | H4C16 | 1:2~1:4 | Negative | Online Inquiry |
KO17184 | H4C16 Knockout cell line (HEK293) | Human | H4C16 | 1:3~1:6 | Negative | Online Inquiry |
KO17185 | H4C16 Knockout cell line (A549) | Human | H4C16 | 1:3~1:4 | Negative | Online Inquiry |
H4C16 Gene Knockout Cell Lines represent a cutting-edge tool for genetic research, created through the precise knockout of the H4C16 gene in a relevant cellular context. These cell lines have been engineered using advanced CRISPR-Cas9 technology, enabling researchers to investigate the functional consequences of gene deletion and elucidate the underlying molecular pathways involved in various biological processes.
The primary function of H4C16 Gene Knockout Cell Lines is to facilitate in vivo and in vitro studies aimed at understanding gene function, interaction networks, and phenotypic outcomes in both health and disease. By eliminating the expression of the H4C16 gene, scientists can assess changes in cellular behavior, gene expression profiles, and metabolic pathways, thereby uncovering insights that are crucial for disease modeling, drug discovery, and therapeutic development.
These cell lines possess significant scientific importance, particularly in fields such as cancer research, immunology, and regenerative medicine. In clinical settings, H4C16 knockouts can support the development of targeted therapies by identifying novel biological targets and elucidating resistance mechanisms, ultimately accelerating the translation of laboratory findings to clinical applications.
Compared to other gene knockout models, H4C16 Gene Knockout Cell Lines offer distinct advantages, including enhanced specificity, reproducibility, and ease of use. Furthermore, the well-characterized nature of these lines allows for streamlined integration into existing experimental workflows, reducing the time and resources commonly expended in research.
Researchers and clinicians will find exceptional value in H4C16 Gene Knockout Cell Lines as they provide a robust platform for groundbreaking studies that can yield critical insights into genetic functions and their implications in disease states. By choosing our product, users gain access to a highly innovative resource developed through expertise in genetic engineering and cell biology, reflecting our commitment to advancing research capabilities and therapeutic advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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