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GRIPAP1 Knockout Cell Lines

Gene: GRIPAP1

Official Full Name: GRIP1 associated protein 1provided by HGNC

Gene Summary: This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). The encoded protein interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function. [provided by RefSeq, Aug 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09514 GRIPAP1 Knockout cell line (HeLa) Human GRIPAP1 1:3~1:6 Negative Online Inquiry
KO09515 GRIPAP1 Knockout cell line (HCT 116) Human GRIPAP1 1:2~1:4 Negative Online Inquiry
KO09516 GRIPAP1 Knockout cell line (HEK293) Human GRIPAP1 1:3~1:6 Negative Online Inquiry
KO09517 GRIPAP1 Knockout cell line (A549) Human GRIPAP1 1:3~1:4 Negative Online Inquiry

Background

GRIPAP1 Gene Knockout Cell Lines are specialized cellular models created to facilitate the study of the GRIPAP1 gene function by silencing its expression through CRISPR/Cas9 technology. These knockout cell lines offer researchers potent tools to investigate the role of GRIPAP1 in various biological processes, including neuronal function, signal transduction, and cellular responses to stress. By eliminating GRIPAP1 expression, these models enable the assessment of downstream effects and interactions, providing insights into its contributions to health and disease pathways.

The functionality of the GRIPAP1 Gene Knockout Cell Lines is based on targeted gene editing, which enables precise alterations in the genome. This approach not only allows researchers to bypass the limitations of traditional methods but also ensures that the resulting cell lines exhibit robust and consistent phenotypic changes. Mechanistically, the silencing of GRIPAP1 can lead to alterations in protein-protein interactions and downstream signaling cascades, opening avenues for exploring its involvement in neurodegenerative diseases and other conditions where dysregulation of cellular signaling is observed.

The scientific importance of these cell lines lies in their versatility across research and clinical applications. They can serve as models for drug screening, functional genomic studies, and elucidation of gene function in pathological contexts. Moreover, the GRIPAP1 knockout lines have significant value in studies aimed at finding therapeutic targets, especially concerning conditions like Alzheimer's disease, where GRIPAP1 expression is influenced.

What sets the GRIPAP1 Gene Knockout Cell Lines apart from existing alternatives is their high specificity and the potential to save valuable research time. Conventional gene silencing methods often suffer from incomplete knockdown, resulting in variable results. In contrast, our knockout lines ensure complete loss of function.

For researchers and clinicians striving for clarity in gene function and functionality assays, the advantages of using GRIPAP1 Gene Knockout Cell Lines are compelling. They provide an indispensable platform for novel discoveries that drive advancements in biomedical research.

At [Your Company Name], we specialize in offering high-quality biological research tools, grounded in innovative technology and a commitment to scientific excellence. Our expertise in gene editing and custom cell line development ensures that you receive reliable products that meet the highest standards for your research needs.

Please note that all services are for research use only. Not intended for any clinical use.

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