Gene: GORASP1
Official Full Name: golgi reassembly stacking protein 1provided by HGNC
Gene Summary: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20736 | GORASP1 Knockout cell line (HeLa) | Human | GORASP1 | 1:3~1:6 | Negative | Online Inquiry |
KO20737 | GORASP1 Knockout cell line (HCT 116) | Human | GORASP1 | 1:2~1:4 | Negative | Online Inquiry |
KO20738 | GORASP1 Knockout cell line (HEK293) | Human | GORASP1 | 1:3~1:6 | Negative | Online Inquiry |
KO20739 | GORASP1 Knockout cell line (A549) | Human | GORASP1 | 1:3~1:4 | Negative | Online Inquiry |
GORASP1 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the systematic study of the GORASP1 gene's functions and interactions. GORASP1, also known as Golgi resident protein, is pivotal in maintaining Golgi structure and vesicular transport within cells. These knockout cell lines are generated using advanced CRISPR/Cas9 gene editing technology, ensuring precise disruption of GORASP1 expression, ultimately enabling researchers to observe the resultant phenotypic changes.
The core function of GORASP1 involves its role in the regulation of Golgi morphology and the trafficking of important cargo proteins. By creating GORASP1 knockout models, researchers can delve into the complexities of Golgi dynamics and its implications in various biological processes, including protein maturation, cellular signaling, and pathogenesis of diseases linked to Golgi dysfunction. These models are invaluable not only for basic research but also in drug discovery and development, allowing scientists to screen potential therapeutics targeting pathways that involve GORASP1-related processes.
Compared to traditional gene knockout methods, our GORASP1 knockout cell lines offer enhanced specificity, reliability, and ease of use. Researchers can easily validate gene function and explore genetic interactions with unparalleled sensitivity. The consistency of our cell lines reduces variability, making experimental outcomes more robust and reproducible.
For researchers and clinicians focused on the intricate mechanisms of vesicular transport, cellular metabolism, or diseases exemplified by Golgi dysfunction, our GORASP1 knockout cell lines present a unique opportunity to generate novel insights and therapeutic targets. With expertise in genetic engineering and a commitment to providing high-quality biological products, our company is dedicated to empowering scientific advances and improving research outcomes through innovative solutions like the GORASP1 knockout cell lines.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.