Gene: GOLM2
Official Full Name: golgi membrane protein 2provided by HGNC
Gene Summary: The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Dec 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02520 | GOLM2 Knockout cell line (HeLa) | Human | GOLM2 | 1:3~1:6 | Negative | Online Inquiry |
KO02521 | GOLM2 Knockout cell line (HCT 116) | Human | GOLM2 | 1:2~1:4 | Negative | Online Inquiry |
KO02522 | GOLM2 Knockout cell line (HEK293) | Human | GOLM2 | 1:3~1:6 | Negative | Online Inquiry |
KO02523 | GOLM2 Knockout cell line (A549) | Human | GOLM2 | 1:3~1:4 | Negative | Online Inquiry |
GOLM2 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of gene function and regulation through the targeted disruption of the GOLM2 gene. These cell lines utilize CRISPR/Cas9 technology, allowing precise editing of the GOLM2 locus, resulting in an absence of functional GOLM2 protein. This gene is implicated in a variety of biological processes, including protein sorting and intracellular transport, making these knockout cell lines invaluable for dissecting the molecular mechanisms underlying these pathways.
The primary function of the GOLM2 Gene Knockout Cell Lines is to provide a robust platform for researchers to investigate the biological effects of GOLM2 deficiency. By utilizing these cell lines, users can perform a myriad of assays, including growth, differentiation, and response to stimuli, thus uncovering insights into GOLM2's role in cellular physiology and pathology. Moreover, these models can serve as a critical resource in the development of therapeutics targeting diseases associated with GOLM2 dysregulation.
The scientific importance of GOLM2 Gene Knockout Cell Lines extends to both research and clinical applications. In research settings, these models can help elucidate the pathways involved in diseases such as cancer or metabolic disorders, where GOLM2 has been shown to play a role. In clinical settings, understanding GOLM2's function could lead to novel therapeutic approaches based on the modulation of its activity.
What sets GOLM2 Gene Knockout Cell Lines apart from alternative models is their high specificity and reproducibility. The precision of CRISPR/Cas9 technology ensures that the gene knockout is both efficient and consistent across different batches, providing reliable data for researchers. Furthermore, the availability of these cell lines allows for their immediate implementation into ongoing research projects, reducing the time needed for traditional knockout experiments.
For researchers and clinicians alike, GOLM2 Gene Knockout Cell Lines hold substantial value, offering a powerful tool for advancing our understanding of cellular processes and disease mechanisms. By using these engineered cells, users can generate critical insights that contribute to the advancement of biomedical science.
Our company has a long-standing commitment to providing high-quality biological products that meet the needs of the scientific community. With a team of experts in genetic engineering and cell line development, we ensure that our offerings, including GOLM2 Gene Knockout Cell Lines, are crafted with precision and a focus on scientific integrity.
Please note that all services are for research use only. Not intended for any clinical use.
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