Gene: GNPNAT1
Official Full Name: glucosamine-phosphate N-acetyltransferase 1provided by HGNC
Gene Summary: Enables identical protein binding activity. Predicted to be involved in UDP-N-acetylglucosamine biosynthetic process. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in endoplasmic reticulum-Golgi intermediate compartment and late endosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17350 | GNPNAT1 Knockout cell line (HeLa) | Human | GNPNAT1 | 1:3~1:6 | Negative | Online Inquiry |
KO17351 | GNPNAT1 Knockout cell line (HCT 116) | Human | GNPNAT1 | 1:2~1:4 | Negative | Online Inquiry |
KO17352 | GNPNAT1 Knockout cell line (HEK293) | Human | GNPNAT1 | 1:3~1:6 | Negative | Online Inquiry |
KO17353 | GNPNAT1 Knockout cell line (A549) | Human | GNPNAT1 | 1:3~1:4 | Negative | Online Inquiry |
GNPNAT1 Gene Knockout Cell Lines are genetically modified cell lines that have been engineered to specifically disrupt the GNPNAT1 gene, which encodes an enzyme involved in nucleotide metabolism. By targeting this gene, researchers can observe the resultant phenotypic effects, facilitating the study of metabolic pathways and the role of nucleotide synthesis in cellular function and disease states.
The key function of GNPNAT1 Gene Knockout Cell Lines lies in their ability to provide a clear model for understanding the implications of GNPNAT1 deficiency. The knockout of this gene is accomplished through advanced techniques such as CRISPR-Cas9, which introduces targeted mutations, leading to the loss of gene expression. As a result, these cell lines can serve as invaluable tools in elucidating the effects of nucleotide imbalance on cellular processes such as proliferation, apoptosis, and differentiation.
In both research and clinical settings, the significance of GNPNAT1 Gene Knockout Cell Lines cannot be overstated. They provide critical insights into genetic disorders associated with nucleotide metabolism and open avenues for discovering therapeutic interventions for diseases such as cancer and metabolic syndromes. Furthermore, by employing these knockout models, researchers can validate drug targets and assess the efficacy of compounds designed to modulate these metabolic pathways.
A distinct advantage of our GNPNAT1 Gene Knockout Cell Lines compared to alternatives is their high specificity and reproducibility. These lines are thoroughly characterized to ensure consistent performance in experimental setups, reducing variability in data and increasing the reliability of results. Additionally, our cell lines are accompanied by comprehensive technical support, ensuring that users can seamlessly incorporate them into their research workflows.
For researchers, clinicians, and biotechnologists, GNPNAT1 Gene Knockout Cell Lines offer a unique opportunity to deepen our understanding of nucleotide metabolism and its implications in health and disease. Leveraging our expertise in genetic engineering and cell line development, our company is committed to providing high-quality biological products that empower scientific discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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