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GNPDA1 Knockout Cell Lines

Gene: GNPDA1

Official Full Name: glucosamine-6-phosphate deaminase 1provided by HGNC

Gene Summary: Glucosamine-6-phosphate deaminase (EC 3.5.99.6) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium (Arreola et al., 2003 [PubMed 12965206]).[supplied by OMIM, Jan 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06943 GNPDA1 Knockout cell line (HeLa) Human GNPDA1 1:3~1:6 Negative Online Inquiry
KO06944 GNPDA1 Knockout cell line (HCT 116) Human GNPDA1 1:2~1:4 Negative Online Inquiry
KO06945 GNPDA1 Knockout cell line (HEK293) Human GNPDA1 1:3~1:6 Negative Online Inquiry
KO06946 GNPDA1 Knockout cell line (A549) Human GNPDA1 1:3~1:4 Negative Online Inquiry

Background

GNPDA1 Gene Knockout Cell Lines are specifically designed biological tools that enable researchers to study the functional role of the GNPDA1 gene in human cellular processes. These cell lines are genetically modified to be deficient in the GNPDA1 gene, which encodes the enzyme glutamine-fructose-6-phosphate transaminase 1, crucial for nucleotide metabolism and cellular energy regulation. By producing knockout variants of this gene, scientists can effectively investigate its contributions to metabolic pathways, cellular proliferation, and differentiation, enhancing our understanding of various physiological and pathophysiological states.

The key function of these knockout cell lines lies in their ability to elucidate the biological consequences of GNPDA1 deficiency. Researchers can observe alterations in metabolic rates, shifts in cellular signaling pathways, and changes in gene expression profiles that occur in the absence of this gene. Mechanistically, the deletion of GNPDA1 allows for the exploration of its role in diseases such as cancer and metabolic disorders, making these cell lines essential for disease modeling and therapeutic target identification.

The scientific importance of GNPDA1 Gene Knockout Cell Lines extends to both basic and applied research settings. They serve as invaluable resources for drug discovery, particularly in gauging the responsiveness of metabolic pathways to therapeutic interventions. Furthermore, their application in translational research aids in the development of personalized medicine strategies by elucidating how genetic variations influence disease susceptibility and treatment outcomes.

When compared to alternative products, GNPDA1 Gene Knockout Cell Lines offer unique advantages, including high specificity in gene targeting and maintained cellular integrity. The reliability and reproducibility of these lines ensure that experimental results are both robust and applicable across various research settings.

For researchers and clinicians focused on understanding the subtleties of gene-function relationships, GNPDA1 Gene Knockout Cell Lines present a unique opportunity to investigate and manipulate critical biological functions. Their capacity to drive innovations in metabolic research and treatment paradigms makes them an essential tool in the modern biological toolkit.

Our company’s extensive experience in developing high-quality genetic models, coupled with advanced robust methodologies, ensures that our GNPDA1 Gene Knockout Cell Lines meet the highest standards of scientific rigor, providing researchers worldwide with reliable and effective resources for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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