Gene: GNG2
Official Full Name: G protein subunit gamma 2provided by HGNC
Gene Summary: This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09027 | GNG2 Knockout cell line (HeLa) | Human | GNG2 | 1:3~1:6 | Negative | Online Inquiry |
KO09028 | GNG2 Knockout cell line (HEK293) | Human | GNG2 | 1:3~1:6 | Negative | Online Inquiry |
KO09029 | GNG2 Knockout cell line (A549) | Human | GNG2 | 1:3~1:4 | Negative | Online Inquiry |
GNG2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the GNG2 gene, which encodes a key component of G-protein signaling pathways. These knockout cell lines serve as valuable tools for researchers investigating the role of GNG2 in various biological processes and diseases. By removing the gene, researchers can study the resulting phenotypic changes and alterations in signaling pathways, providing insights into the complex mechanisms that govern cellular behavior, communication, and response to stimuli.
The primary function of GNG2 Gene Knockout Cell Lines is to facilitate the investigation of G-protein-coupled receptor (GPCR) signaling mechanisms. The GNG2 protein is part of the Gβγ subunit complex, which plays a pivotal role in transmitting signals from activated GPCRs to intracellular effectors. By utilizing these knockout cell lines, scientists can elucidate the contributions of GNG2-dependent signaling in a wide range of physiological and pathological contexts, including cancer biology, neurology, and immunology.
The scientific significance of GNG2 Gene Knockout Cell Lines extends to their applications in drug discovery and therapeutic development. Understanding GNG2's role in signaling pathways may lead to new therapeutic targets in diseases where GPCR signaling is dysregulated. By employing these cell lines, researchers can screen for compounds that specifically modulate GPCR pathways influenced by GNG2, thus accelerating the drug development process.
What sets GNG2 Gene Knockout Cell Lines apart from alternative platforms is their precision in gene editing and the reliability of the knockout phenotype. Unlike conventional methods, our cell lines have undergone stringent validation processes to confirm the absence of GNG2 expression. This high level of specificity ensures that any observed biological effects can be directly attributed to GNG2 disruption, minimizing confounding variables and enhancing experimental rigor.
For researchers, clinicians, and biopharmaceutical companies, investing in GNG2 Gene Knockout Cell Lines means gaining access to a robust model system that drives innovation in signaling research and therapeutic exploration. Our commitment to excellence in genetic engineering and cell line development translates into reliable and reproducible research tools that empower scientists to advance their studies with confidence and clarity.
With years of expertise in the field of genetic engineering and a deep understanding of cellular biology, our company is dedicated to providing high-quality biological products tailored to meet the needs of the research community. GNG2 Gene Knockout Cell Lines exemplify our mission to support pioneering research and foster scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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