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GNG11 Knockout Cell Lines

Gene: GNG11

Official Full Name: G protein subunit gamma 11provided by HGNC

Gene Summary: This gene is a member of the guanine nucleotide-binding protein (G protein) gamma family and encodes a lipid-anchored, cell membrane protein. As a member of the heterotrimeric G protein complex, this protein plays a role in this transmembrane signaling system. This protein is also subject to carboxyl-terminal processing. Decreased expression of this gene is associated with splenic marginal zone lymphomas. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09015 GNG11 Knockout cell line (HeLa) Human GNG11 1:3~1:6 Negative Online Inquiry
KO09016 GNG11 Knockout cell line (HEK293) Human GNG11 1:3~1:6 Negative Online Inquiry
KO09017 GNG11 Knockout cell line (A549) Human GNG11 1:3~1:4 Negative Online Inquiry

Background

GNG11 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the investigation of the GNG11 gene's function and its role in cellular signaling pathways. By employing CRISPR-Cas9 gene editing technology, these knockout cell lines effectively eliminate the GNG11 gene, providing researchers with a powerful tool to analyze the downstream effects of its absence on cellular behavior, signal transduction, and pathogenic mechanisms.

The primary function of GNG11 is to encode a subunit of G-proteins that are pivotal in transmitting signals from various cell surface receptors into the cell's interior. This key role in signal transduction highlights the gene's significance in numerous physiological processes, including cell proliferation, differentiation, and migration, as well as its involvement in various diseases. Utilizing GNG11 knockout cell lines, researchers can unravel the gene's functional contributions and investigate how its dysregulation may influence oncogenic processes or other pathophysiological conditions.

The scientific importance of these cell lines extends beyond basic research; they play a critical role in drug discovery and development, allowing for the identification of potential therapeutic targets and the evaluation of drug efficacy in a controlled environment. Furthermore, the versatility of GNG11 knockout cell lines makes them suitable for a wide array of applications, from pharmacological studies to gene therapy explorations.

Compared to alternative models, GNG11 knockout cell lines stand out for their specificity and reliability. Conventional methods, such as chemical inhibitors or RNA interference, may yield off-target effects or incomplete gene silencing. In contrast, the CRISPR-Cas9 system employed ensures precise and complete knockout of the target gene, providing a pure model for studying the associated phenotypes.

For researchers and clinicians alike, the value of GNG11 Gene Knockout Cell Lines lies in their ability to deliver consistent results that enhance reproducibility and reliability. By enabling deeper insights into GNG11's role in various biological processes, these cell lines empower scientific inquiry and innovation.

Our company is at the forefront of biotechnological advancements, committed to equipping researchers with cutting-edge products that facilitate groundbreaking discoveries in molecular biology. We pride ourselves on our expertise in creating high-quality biological tools, such as the GNG11 Gene Knockout Cell Lines, which are essential for driving research excellence and advancing healthcare solutions.

Please note that all services are for research use only. Not intended for any clinical use.

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