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GLIPR1 Knockout Cell Lines

Gene: GLIPR1

Official Full Name: GLI pathogenesis related 1provided by HGNC

Gene Summary: This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31331 GLIPR1 Knockout cell line (HeLa) Human GLIPR1 1:3~1:6 Negative Online Inquiry
KO31332 GLIPR1 Knockout cell line (HCT 116) Human GLIPR1 1:2~1:4 Negative Online Inquiry
KO31333 GLIPR1 Knockout cell line (HEK293) Human GLIPR1 1:3~1:6 Negative Online Inquiry
KO31334 GLIPR1 Knockout cell line (A549) Human GLIPR1 1:3~1:4 Negative Online Inquiry

Background

GLIPR1 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to facilitate the study of the GLIPR1 gene, which is implicated in various biological pathways, including tumor suppression and cellular signaling mechanisms. These knockout lines are generated through advanced CRISPR-Cas9 gene-editing technology, which effectively eliminates the GLIPR1 gene function, providing a powerful tool for researchers aiming to elucidate the gene's role within cellular contexts.

The key functions of these cell lines lie in their ability to mimic disease states by providing insights into how the absence of GLIPR1 affects cellular behavior, proliferation, and the response to therapeutic agents. By studying these knockout models, researchers can investigate how GLIPR1 influences tumorigenesis and other pathological conditions, enhancing our understanding of cancer biology and potential therapeutic targets.

From a scientific perspective, GLIPR1 Gene Knockout Cell Lines serve critical applications in both research and clinical settings. They can be used in drug screening assays to identify compounds that may bypass the functions of the GLIPR1 gene, as well as in studies of molecular mechanisms underlying various diseases. Additionally, these knockout lines can aid in the validation of biomarkers related to GLIPR1 in cancer diagnostics.

One of the specific advantages of our GLIPR1 Gene Knockout Cell Lines is their ease of use and reproducibility, which surpasses that of conventional knockout methods. Unlike traditional approaches, our meticulously developed cell lines have undergone thorough validation to ensure consistent performance, allowing researchers to confidently interpret results.

The value of GLIPR1 Gene Knockout Cell Lines to researchers and clinicians lies in their ability to accelerate research outcomes, streamline experimental workflows, and provide a deeper understanding of the molecular mechanisms at play in critical health issues. This leads to innovation in therapeutic strategies and facilitates the quest for new treatments.

With years of expertise in genetic engineering and a commitment to empowering scientific discovery, our company proudly offers these state-of-the-art biological products. We are dedicated to equipping researchers and clinicians with the resources they need to further the frontiers of biomedical knowledge.

Please note that all services are for research use only. Not intended for any clinical use.

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