Gene: GDF11
Official Full Name: growth differentiation factor 11provided by HGNC
Gene Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32131 | GDF11 Knockout cell line (HeLa) | Human | GDF11 | 1:3~1:6 | Negative | Online Inquiry |
KO32132 | GDF11 Knockout cell line (HCT 116) | Human | GDF11 | 1:2~1:4 | Negative | Online Inquiry |
KO32133 | GDF11 Knockout cell line (HEK293) | Human | GDF11 | 1:3~1:6 | Negative | Online Inquiry |
KO32134 | GDF11 Knockout cell line (A549) | Human | GDF11 | 1:3~1:4 | Negative | Online Inquiry |
GDF11 Gene Knockout Cell Lines are engineered cellular models designed to facilitate the study of the growth differentiation factor 11 (GDF11) gene's functions and its role in various biological processes. These cell lines have undergone precise genetic modifications through CRISPR-Cas9 technology, effectively disabling the GDF11 gene. This knockout enables researchers to elucidate the molecular pathways influenced by GDF11, particularly in contexts such as aging, neurogenesis, and cardiovascular development.
The primary function of these knockout cell lines is to provide a clear platform for researchers to investigate the downstream effects of GDF11 absence. By comparing these genetically altered cells with their wild-type counterparts, scientists can observe differences in cellular behavior, signaling pathways, and phenotypic characteristics. This is particularly important as GDF11 has been implicated in regenerative biology, suggesting that its modulation could lead to advancements in therapeutic strategies for age-related diseases.
The scientific importance of GDF11 Gene Knockout Cell Lines extends into both research and clinical realms. They serve as invaluable tools for understanding GDF11's role in various pathological conditions and for the development of novel treatment paradigms. Additionally, these cell lines can be utilized in drug screening assays to test compounds targeting the GDF11-related pathways, thereby accelerating translational research efforts.
What sets GDF11 Gene Knockout Cell Lines apart from alternative models is their specific knockdown capability on the GDF11 gene, providing a more precise approach to studying this factor's unique contributions. Furthermore, their robust performance and reproducibility make them an essential addition to any laboratory focusing on cancer biology, stem cell research, or regenerative medicine.
Researchers and clinicians can greatly benefit from these knockout cell lines, as they are designed to reduce experimental variability while enhancing data reliability. By utilizing GDF11 Gene Knockout Cell Lines in your investigations, you can uncover critical insights that drive scientific progress and potentially lead to innovative solutions in health management.
Our company prides itself on its expertise in developing high-quality biological products, ensuring that researchers have access to cutting-edge tools that empower their work and elevate the standards of scientific inquiry.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.