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GAL Knockout Cell Lines

Gene: GAL

Official Full Name: galanin and GMAP prepropeptideprovided by HGNC

Gene Summary: This gene encodes a neuroendocrine peptide that is widely expressed in the central and peripheral nervous systems and also the gastrointestinal tract, pancreas, adrenal gland and urogenital tract. The encoded protein is a precursor that is proteolytically processed to generate two mature peptides: galanin and galanin message-associated peptide (GMAP). Galanin has diverse physiological functions including nociception, feeding and energy homeostasis, osmotic regulation and water balance. GMAP has been demonstrated to possess antifungal activity and hypothesized to be part of the innate immune system. [provided by RefSeq, Jul 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00291 GAL gRNA1-gRNA2 KO plasmid GAL $850
KO00659 GAL Knockout cell line(HCT 116) Human GAL 1:2~1:4 Negative Online Inquiry
KO00677 GAL Knockout cell line(293T) Human GAL 1:3~1:6 Negative Online Inquiry
KO05187 GAL Knockout cell line (HeLa) Human GAL 1:3~1:6 Negative Online Inquiry
KO05188 GAL Knockout cell line (HEK293) Human GAL 1:3~1:6 Negative Online Inquiry
KO05189 GAL Knockout cell line (A549) Human GAL 1:3~1:4 Negative Online Inquiry

Background

GAL Gene Knockout Cell Lines are genetically engineered cellular models designed to study the functional effects of the GAL gene on various biological processes. By employing CRISPR-Cas9 technology, these cell lines achieve precise gene knockout, enabling researchers to disrupt the expression of the GAL gene effectively. This creates a valuable platform for investigating the gene's role in metabolic pathways, cellular responses, and disease mechanisms.

The primary function of GAL Gene Knockout Cell Lines is to provide insights into the physiological and pathological implications of the GAL gene's absence. The knockout model facilitates the analysis of downstream signaling pathways and gene interactions, making it an essential tool for assessing how loss of function may contribute to conditions such as metabolic disorders and cancer. The unique mechanism of action allows for the observation of phenotypic changes in a controlled environment, which is crucial for hypothesis testing in experimental research.

In terms of scientific importance, GAL Gene Knockout Cell Lines have applications across various fields, including pharmacology, toxicology, and genetics. They are instrumental in drug discovery processes, enabling the identification of target-specific therapies and the evaluation of treatment efficacy in context to GAL gene functions. Moreover, these cell lines can serve as a benchmark for developing gene therapies and understanding complex genetic diseases.

What sets GAL Gene Knockout Cell Lines apart from alternative models is their high specificity and reproducibility, which ensures reliable results across different laboratories. By utilizing a robust and widely accepted gene-editing technique, these cell lines provide a more accurate representation of biological processes than traditional knockout models. Additionally, their ease of use and adaptability to various culturing conditions enable researchers to incorporate them seamlessly into existing workflows.

For researchers and clinicians, the value proposition of GAL Gene Knockout Cell Lines lies in their ability to advance understanding of gene function and disease mechanisms while facilitating the development of innovative therapeutic strategies. With a focus on quality and cutting-edge technology, our company is committed to delivering reliable, high-performance biological products that empower scientific exploration and improve clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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