Home / FZD8 Knockout Cell Lines

FZD8 Knockout Cell Lines

Gene: FZD8

Official Full Name: frizzled class receptor 8provided by HGNC

Gene Summary: This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11751 FZD8 Knockout cell line (HeLa) Human FZD8 1:3~1:6 Negative Online Inquiry
KO11752 FZD8 Knockout cell line (HEK293) Human FZD8 1:3~1:6 Negative Online Inquiry
KO11753 FZD8 Knockout cell line (A549) Human FZD8 1:3~1:4 Negative Online Inquiry

Background

FZD8 Gene Knockout Cell Lines are genetically engineered cell lines that have undergone targeted deletion of the FZD8 gene, a member of the Frizzled receptor family that plays a critical role in the Wnt signaling pathway. This pathway is essential for numerous biological processes, including cell proliferation, differentiation, and tissue homeostasis. The knockout of FZD8 allows researchers to study the specific contributions of this receptor in various cellular functions and its implications in developmental biology and disease mechanisms.

The primary function of FZD8 is to mediate Wnt signaling, an important pathway in embryonic development and stem cell maintenance. By utilizing FZD8 Gene Knockout Cell Lines, scientists can dissect the role of FZD8 in Wnt-related processes, effectively uncovering how its absence affects cellular behavior, gene expression, and overall signaling cascades. These knockout models are invaluable for investigating diseases such as cancer, where aberrant Wnt signaling is often implicated.

The scientific significance of FZD8 Gene Knockout Cell Lines extends to both fundamental research and potential therapeutic applications. They can be employed in drug discovery, providing insights into how modulation of the Wnt pathway may offer novel treatment avenues for various disorders. These cell lines represent a powerful tool for elucidating the complexities of the Wnt signaling network and its involvement in both normal and pathological states.

One of the unique selling points of our FZD8 Gene Knockout Cell Lines is their precision and reliability, achieved through advanced CRISPR/Cas9 gene editing technology. Unlike traditional methods, which may introduce a range of mutations, our knockout lines ensure complete and consistent deletion of the target gene, enabling reproducible experimental results. This accuracy provides researchers with confidence in their experimental outcomes and hypotheses.

For researchers and clinicians alike, the value of FZD8 Gene Knockout Cell Lines lies in their ability to facilitate innovative research into cellular signaling pathways, advancing our understanding of complex biological processes. These models not only streamline experimental design but also enhance the potential for discovering new therapeutic strategies.

At [Your Company Name], we pride ourselves on our deep expertise in gene editing technologies and commitment to providing high-quality biological products. Our FZD8 Gene Knockout Cell Lines are a testament to our dedication to supporting scientific advancement and research excellence.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.