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FSCN2 Knockout Cell Lines

Gene: FSCN2

Official Full Name: fascin actin-bundling protein 2, retinalprovided by HGNC

Gene Summary: This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28823 FSCN2 Knockout cell line (HCT 116) Human FSCN2 1:2~1:4 Negative Online Inquiry

Background

FSCN2 Gene Knockout Cell Lines are genetically engineered cell lines designed to lack functional FSCN2, also known as Fascin 2, which is a protein involved in the regulation of actin filaments and cell motility. These knockout models are produced through advanced CRISPR-Cas9 or other gene-editing techniques, ensuring precise elimination of the FSCN2 gene. This dedicated removal allows for in-depth study of the cellular functions modulated by FSCN2, particularly its role in cytoskeletal dynamics, cellular adhesion, and migration.

The key mechanisms of action revolve around the disruption of actin filament organization, which FSCN2 typically stabilizes and bundles during cellular processes. By utilizing these knockout cell lines, researchers can elucidate the pathways influenced by FSCN2, assess the impact on cell morphology and motility, and investigate its involvement in pathological states such as cancer metastasis or neurodegeneration.

In terms of scientific importance, the FSCN2 Gene Knockout Cell Lines serve as invaluable tools in both basic and applied research settings. They facilitate the exploration of cell behavior in human disease models while leading to insights that can drive therapeutic innovations. Additionally, these cell lines are integral in drug discovery processes, allowing scientists to assess the efficacy of potential compounds against specific cellular responses mediated by FSCN2.

What sets our FSCN2 Gene Knockout Cell Lines apart from alternatives is the rigorous validation of gene editing efficiency, coupled with stringent quality control measures, ensuring reproducibility and reliability in experimental settings. Unlike conventional cell lines that may possess residual gene expression, our knockout models guarantee a complete absence of the target gene, providing researchers with confidence in their results.

For researchers and clinicians aiming to understand the intricacies of cellular movement and its implications in health and disease, the FSCN2 Gene Knockout Cell Lines represent a breakthrough resource. Equipped with these lines, you can accelerate your research outcomes, paving the way for innovative discoveries.

At [Your Company Name], we are dedicated to empowering the scientific community by providing high-quality, precise biological products tailored to meet the evolving needs of researchers and clinicians. Our commitment to excellence is anchored in our expertise and deep understanding of molecular biology, enabling us to support transformative research with cutting-edge tools.

Please note that all services are for research use only. Not intended for any clinical use.

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