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FIGNL1 Knockout Cell Lines

Gene: FIGNL1

Official Full Name: fidgetin like 1provided by HGNC

Gene Summary: This gene encodes a member of the AAA ATPase family of proteins. The encoded protein is recruited to sites of DNA damage where it plays a role in DNA double-strand break repair via homologous recombination. This protein has also been shown to localize to the centrosome and inhibit ciliogenesis, and may regulate the proliferation and differentiation of osteoblasts. [provided by RefSeq, Oct 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17595 FIGNL1 Knockout cell line (HeLa) Human FIGNL1 1:3~1:6 Negative Online Inquiry
KO17596 FIGNL1 Knockout cell line (HCT 116) Human FIGNL1 1:2~1:4 Negative Online Inquiry
KO17597 FIGNL1 Knockout cell line (HEK293) Human FIGNL1 1:3~1:6 Negative Online Inquiry
KO17598 FIGNL1 Knockout cell line (A549) Human FIGNL1 1:3~1:4 Negative Online Inquiry

Background

FIGNL1 Gene Knockout Cell Lines are a revolutionary tool in the field of molecular biology, specifically designed to facilitate the in-depth study of the FIGNL1 gene's function and its implications in various biological processes. These cell lines have been meticulously engineered using CRISPR/Cas9 technology to create stable knockout clones that exhibit a complete absence of FIGNL1 expression, allowing researchers to observe the resulting phenotypic changes and elicit insights into the gene's role in cellular mechanisms.

The key function of FIGNL1, which encodes a protein implicated in DNA repair, cell cycle regulation, and responses to oxidative stress, is critical for maintaining genomic stability. By utilizing these knockout cell lines, scientists can investigate the effects of FIGNL1 deficiency on various biological pathways, including those involved in cancer proliferation and progression, ultimately shedding light on the gene's significance in health and disease.

The scientific importance of FIGNL1 Gene Knockout Cell Lines lies in their broad range of applications across research and clinical settings. They serve as invaluable models for studying tumor biology, drug resistance mechanisms, and the cellular response to DNA damaging agents. Furthermore, these cell lines can substantially enhance translational research, allowing for the identification of potential therapeutic targets related to diseases associated with FIGNL1 dysfunction.

What sets FIGNL1 Gene Knockout Cell Lines apart from alternative products is their high reliability, consistency, and ease of use. The precise editing capabilities of the CRISPR technology ensure minimal off-target effects, leading to high confidence in data derived from experiments. Additionally, the availability of well-characterized, functional KO models supports reproducibility across various laboratories, enhancing collaborative research efforts.

For researchers, clinicians, and industries focused on advancing genetic studies, the FIGNL1 Gene Knockout Cell Lines provide an essential resource that bridges basic science with clinical applications. The insights gained from these models can directly inform the development of novel therapeutic strategies and improve our understanding of disease biology.

Our company brings years of expertise in the field of genetic engineering and cell line development to deliver top-tier biological products. We are committed to supporting the scientific community with tools that empower innovative research and pave the way for future breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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