Gene: FGF5
Official Full Name: fibroblast growth factor 5provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10798 | FGF5 Knockout cell line (HEK293) | Human | FGF5 | 1:3~1:6 | Negative | Online Inquiry |
FGF5 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically modified to lack the Fibroblast Growth Factor 5 (FGF5) gene. This knockout approach serves as a powerful tool for researchers aiming to study the role of FGF5 in various biological processes, including cell growth, differentiation, and tissue repair. By eliminating FGF5 expression, these cell lines provide a unique opportunity to investigate the gene's contributions to developmental biology and its implications in disorders such as muscular dystrophies and fibrotic diseases.
The key function of FGF5 is its role in the regulatory pathways governing cell proliferation and survival. By studying FGF5 knockout cells, researchers can elucidate the underlying mechanisms through which FGF5 influences cellular behavior, including its impact on signaling pathways related to apoptosis and tissue homeostasis. This is particularly important in understanding not only normal physiological processes but also the pathological conditions resulting from dysregulation of FGF signaling.
The scientific importance of FGF5 Gene Knockout Cell Lines extends into both fundamental research and clinical applications. In research settings, these models facilitate the exploration of FGF5's role in oncogenesis and tissue regeneration, allowing scientists to assess potential therapeutic targets. Clinically, understanding the mechanism of action of FGF5 can lead to the development of novel treatment strategies for conditions linked to aberrant FGF signaling.
What sets our FGF5 Gene Knockout Cell Lines apart from alternatives is their high degree of precision in gene editing, achieved using advanced CRISPR/Cas9 technology, ensuring complete loss of function. Additionally, the cell lines undergo rigorous characterization and validation processes, confirming their utility and reliability for experimental purposes. In comparison to other models, our products offer uniformity in results and reduce variability, making them exceptionally valuable for reproducibility in scientific research.
For researchers and clinicians, the value of utilizing FGF5 Gene Knockout Cell Lines lies in their ability to provide significant insights into the role of FGF5 in health and disease. This knowledge can drive innovative research directions and inform therapeutic approaches, paving the way for advancements in regenerative medicine and cancer therapies.
Our company specializes in delivering cutting-edge biological products backed by extensive expertise in genetic engineering and cellular sciences. We are committed to providing high-quality, reliable research tools that enhance scientific discovery and contribute to the advancement of healthcare solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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