Gene: FGF11
Official Full Name: fibroblast growth factor 11provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05071 | FGF11 Knockout cell line (HeLa) | Human | FGF11 | 1:3~1:6 | Negative | Online Inquiry |
KO05072 | FGF11 Knockout cell line (HCT 116) | Human | FGF11 | 1:2~1:4 | Negative | Online Inquiry |
KO05073 | FGF11 Knockout cell line (HEK293) | Human | FGF11 | 1:3~1:6 | Negative | Online Inquiry |
FGF11 Gene Knockout Cell Lines are a specialized biological product designed to facilitate in-depth research into the fibroblast growth factor (FGF) signaling pathways and their implications in cellular processes. These cell lines have been genetically engineered to disrupt the fibroblast growth factor 11 (FGF11) gene, a member of the FGF family known for its role in neural and cardiac development. The knockout mechanism is achieved using precise gene-editing techniques such as CRISPR/Cas9, resulting in targeted mutations that provide researchers with invaluable models for studying FGF11’s functional contributions.
The fundamental function of these cell lines is to enable the exploration of FGF11-related signaling pathways, which are implicated in various pathological conditions, including cardiac hypertrophy and neurodevelopmental disorders. By eliminating the FGF11 gene, researchers can clearly delineate the gene's role in physiological and pathological processes, allowing for more accurate modeling of diseases and the testing of therapeutic interventions.
The scientific importance of FGF11 Gene Knockout Cell Lines extends to both academic research and clinical applications. They serve as critical tools for drug discovery, cellular biology studies, and translational research, particularly in understanding the molecular mechanisms behind developmental biology and disease pathogenesis. Furthermore, their use in high-throughput screening offers significant promise in identifying novel pharmacological targets.
Unlike traditional cell lines that express the FGF11 gene, the knockout lines eliminate potential confounding factors associated with gene expression variability. This specificity enhances experimental reliability and reproducibility, making them a superior alternative for targeted studies. Additionally, the FGF11 Gene Knockout Cell Lines are optimized for ease of use, featuring robust growth and adaptability to various culture conditions.
Researchers and clinicians looking to deepen their understanding of FGF signaling and its diverse biological implications will find immense value in these knockout lines. The ability to study the absence of FGF11 in a controlled environment positions users to gain insights that drive innovation in both therapeutic approaches and fundamental biology.
Our company specializes in the development of state-of-the-art genetic tools and bioresearch solutions. With a commitment to excellence in product quality and support, we provide the essential resources needed for impactful biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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