Gene: FERMT1
Official Full Name: FERM domain containing kindlin 1provided by HGNC
Gene Summary: This gene encodes a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. The encoded protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix. Mutations in this gene have been linked to Kindler syndrome. [provided by RefSeq, Dec 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17629 | FERMT1 Knockout cell line (HeLa) | Human | FERMT1 | 1:3~1:6 | Negative | Online Inquiry |
KO17630 | FERMT1 Knockout cell line (HCT 116) | Human | FERMT1 | 1:2~1:4 | Negative | Online Inquiry |
KO17631 | FERMT1 Knockout cell line (HEK293) | Human | FERMT1 | 1:3~1:6 | Negative | Online Inquiry |
KO17632 | FERMT1 Knockout cell line (A549) | Human | FERMT1 | 1:3~1:4 | Negative | Online Inquiry |
FERMT1 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the function of the FERMT1 (fermitin family member 1) gene, known for its critical role in cellular adhesion processes and signal transduction pathways. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines enable researchers to create precise genetic disruptions in the FERMT1 gene, allowing for a thorough investigation of the gene's biological contributions and its implications in various disease models.
The primary function of the FERMT1 gene is to encode a protein involved in integrin signaling, which is essential for cell migration, differentiation, and the maintenance of tissue architecture. By knocking out this gene, researchers can elucidate the downstream effects on cell behavior, providing insights into mechanisms of diseases such as cancer, where altered cell adhesion and motility are critical factors.
In both research and clinical settings, FERMT1 Gene Knockout Cell Lines have significant scientific importance as they offer a reliable tool to explore key biological pathways and validate drug targets. The insights gained from such studies can drive forward the development of targeted therapies and contribute to a better understanding of disease mechanisms.
One of the unique selling points of our FERMT1 Gene Knockout Cell Lines is their high specificity and reproducibility, along with a user-friendly protocol that allows for easy integration into existing experimental workflows. Compared to traditional knockdown approaches, these knockout cell lines provide more robust and lasting genetic modifications that minimize off-target effects, enhancing the reliability of experimental outcomes.
For researchers and clinicians looking to deepen their understanding of cellular dynamics and disease pathology, our FERMT1 Gene Knockout Cell Lines represent an invaluable resource. They not only facilitate groundbreaking discoveries but also pave the way for innovative therapeutic strategies.
Our company prides itself on leveraging advanced genetic engineering technologies and a deep understanding of molecular biology, ensuring the highest quality products and support for our customers. With our expertise, we are committed to empowering researchers with the tools they need to push the boundaries of scientific knowledge.
Please note that all services are for research use only. Not intended for any clinical use.
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